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    Softgel Coatings

    Customized solutions for the effective coatings of softgels to provide enteric sustained release and moisture protection

    Functional coating is one way of modifying drug release from the softgel. In many cases the drug product needs to protected from acid attack in the stomach and enteric release coatings provide protection from this occurring. Also, sustained release coatings can provide a multitude of modified release drug profiles for the softgel. The moisture barrier coating can provide long term stability for moisture sensitive APIs. BASF has a comprehensive portfolio of coating solutions to provide these functionalities. Our technical experts can help customize formulations and coating processes for your particular product needs.

    Global network of experts in softgel coatings
    Comprehensive portfolio of coating solutions for enteric and sustained release and moisture protection
    Technical and application service to develop coating formulation and process for successful commercialization


    Best Practices to Overcome Softgel Coating Challenges

    Soft gelatin capsules (softgels) have become an increasingly popular method for the delivery of pharmaceuticals and dietary supplements due to to the ability to encapsulate sensitive compounds, accurately deliver potent molecules, and directly appeal to the consumer. However, applying a functional coating to softgels is a challenging endeavor requiring precise formulation and finely tuned processing parameters that only recently have been explored. In this webcast,  pharmaceutical scientists and formulators will learn about key aspects of successful softgel coating processes. Discussion topics include:


    The Use of Polyvinyl Acetate Dispersion for Coating Soft Gelatin Capsules

    Developing controlled release drug products for high-dose and highly water soluble actives can be challenging. One of the examples is the enteric coated Omega-3 softgel capsules for the dietary supplement market. Kollicoat® SR 30D is a 30% aqueous dispersion of Polyvinyl Acetate typically used to provide sustained release coating for various dosage forms. In this study, Ascorbic acid 500mg soft gel capsules were coated with Kollicoat® SR 30D to achieve controlled release.


    Enhancing protective properties of an instant release film-coating formulation

    This work was conducted to investigate the impact of copovidone on the protective properties of and instant release (IR) coat.

    Application Guide

    Gastric-resistant coating of soft gelatin capsules

    ExActConcepts – generic drug formulation for Omega 3 (Fish) oil: This formulation concept effectively combines no fish burp and fast release of the Omega-3 in the gastro intestinal tract.

    Product Overview

    Focusing on your needs with platform solutions

    This brochure presents an overview of our leading-edge products, grouped in the following platforms: Softgels, Instant and Modified Release, Solubilization, Skin Delivery, Biologics Solutions.