Direct compression (DC) is the most economic way to produce a tablet as it is the shortest and most direct way to get from powder mix to final dosage form. BASF offers all functional excipients to successfully develop a DC process for your drug, including key elements like appropriate binder and lubricant.
Direct compression of solid oral dosage forms – a full range of functional solutions
Today, direct compression plays a key role in the pharmaceutical industry as the continuing trend towards generics requires manufacturers to design their production processes as efficient as possible. This is what direct compression delivers – formulation components are homogenized by mixing and then directly compressed into the final dosage form.
However, in order to achieve a robust and lasting dosage form, the to be compressed functional components used in the mix must exhibit good flowability and compressibility. And this factor gets more important in case
- the amount of functional excipient in the formulation is reduced, i.e. due to a required high drug load, or
- the drug itself is very poorly flowable or compressible.
This is why we offer a range of high to highly effective direct compression binders, disintegrants and lubricants that will provide you all the design space you need for your formulation.
And if you are working on a project where time-to-market is absolutely critical, we offer specialized ready-to-use premixes for tablets, orally disintegrating tablets and other dosage forms that will enable you to take the fast track towards your direct compression process.
Discover more about solutions for direct compression
Formulation Examples of various tablet forms