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    Functional solutions for formulations with enteric drug release

    When the active ingredient is not supposed to be released in the stomach, a formulator will design his dosage form with an enteric release profile. BASFs enteric release excipients offer maximum functionality while being the most easy-to-apply.

    With an enteric release profile, the drug release of the drug is delayed until the dosage form reaches the intestine. This release characteristic is typically chosen either to protect the stomach from a drug (i.e. acetylsalicylic acid), or to protect a sensitive drug from the acids in the stomach (i.e. most proton pump inhibitors). Enteric release profiles are also used for omega-3 softgel capsules in order to prevent dissolution of the capsules in the stomach, potentially leading to unpleasant burps. And in combination with effective sustained release excipients like Kollicoat® SR 30 D, enteric release polymers can also be used for delayed sustained drug release starting only in the intestine.

    BASF offers the most widely used functional excipient for enteric release profiles in both aqueous and powderous form. Either one of them offers simple processing and reliable functional results.

    BASF materials for enteric release offer all that you expect from a functional excipient
    Fully reliable functional performance for a maximum of patient security and compliance
    High functional efficiency –
    achieving the desired release effect already at low use
    Easy
    processing

    Webinar

    Product innovation on modified release coatings (sustained release and enteric coatings)

    Developing modified coatings that produce a reliable and stable release is still a challenge. Only a few polymers - polyvinylacetate, ethylcellulose and methacrylates - are suitable for this purpose and have very different characteristics. In this webinar, you will gain an in-depth knowledge about the relevant requirements for modified release coatings and how they can be fulfilled, for instance by choosing a suitable polymer, the proper formulation and the best process parameters.

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