Topical gel formulations are of increasing interest in the dermatology industry. Gel formulations are typically transparent or translucent, water-based semisolids with good spreading properties and pleasing aesthetic characteristics.
Gels derive their consistency and rheological properties from polymers that can swell in water and then interact in such a way as to thicken the water and increase viscosity. Polymers may interact physically, by chain entanglement, or by ionic or hydrophobic/hydrophilic interactions. In each case, the polymers form a matrix that increases the viscosity of the water and allows for (1) physical stabilization and prevention of migration of suspended API crystals, (2) maintenance of product homogeneity throughout the shelf life, (3) clean, no drip, no mess transfer of the product from the primary package to the skin surface and (4) easy spreading and acceptable aesthetics.
BASF offers broad portfolio of excipients for topical formulations enabling you to create the ideal skin delivery solution for your gel formulation. We are committed to maintaining the highest level of quality. At the same time, we have focused on improving the mildness of formulations. And by extensively analyzing, refining and enhancing the sensorial effects of each ingredient class, we can help you to create products that increase patient compliance.
Some of the key functional excipients offered by BASF include:
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