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    Instant Release



    Functional solutions for formulations with instant drug release

    An instant release profile enables the immediate beginning of the dissolving process of a dosage form once it has been swallowed and reached the patient’s stomach. BASF offers highly functional, instant release polymers.

    Instant drug release is the most commonly used release profile for solid oral dosage forms. It means to release the active ingredient immediately when it reaches the stomach. Since most solid dosage forms, particularly tablets, receive a coating to provide them with basic protection from environmental factors as well as pleasant appearance, a formulator needs to make sure that this coating dissolves just as fast.

    We offer a comprehensive range of functional materials that provide exactly this characteristic. Whether you are looking for a high efficiency instant release coating, for moisture protection or for easy-to-apply yet very effective taste-masking – we have a solution.

    BASFs instant release solutions are characterized by
    High efficiency, thus low cost-of-ownership
    Robust processing and easy-of-use
    Applicability in aqueous media, no organic solvents required

    And of course, we also offer a wide range of functional solutions to create instant release pores in sustained release matrices or coatings.

    Webinar

    BASF pharma solutions for orally disintegrating tablets

    ODTs are becoming increasingly popular for various reasons. For the consumer or patient, they offer a much more convenient administration, while healthcare companies can use them to differentiate their offer by creating line extensions. In this webinar you will learn about three approaches to develop an ODT – direct compression, granulation & tableting and ready-to-use - and the pros and cons they offer. We will provide guidance on how to choose the right approach for your project, and will support this with a case study as well as an in-depth look at the selection of specific formulation components.

    Article

    A recent advancement in orally disintegrating formulations

    Orally disintegrating tablets (ODT) or sublingual technologies have drawn attention in the industry as a promising approach to deliver drugs in life cycle management to a wide range of the patient population. Those technologies are also aimed at patients incapable of swallowing pills, especially in pediatric and geriatric populations. The criteria for rapid dissolution and onset of active ingredients in an ODT dosage depends on the performances of individual excipients which must qualify 3 unique criteria: (i) hydrophilic in nature, (ii) dissolves quickly with good mouth feel, and (iii) is highly compressible. Identifying such excipients and/or technologies to meet these criteria could be challenging, especially to overcome the drug’s loading and stability.