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    Excipients for Drug Formulation Kollicoat® MAE 100-55

    Kollicoat® MAE 100-55

    A complete match – just better. Kollicoat® MAE 100-55 combines two things hard to bring together – it can directly exchange the comparable pH 5.5 enteric release coating polymer in your commercial formulations, and still bring significant handling improvement to your operators because it does not dust at all.

    Kollicoat® MAE 100-55 is the latest addition to our comprehensive portfolio of functional excipients in our Instant & Modified Release Platform. It extends our offer of pH >5.5 enteric release products based on methacrylic acid-ethylacrylate copolymer, providing you even more flexibility.

    Why choose Kollicoat® MAE 100-55
    Direct substitution in commercial formulations
    Easier handling due to dust-free material
    Compliant with respective monographs

    Kollicoat® MAE 100-55
    (non-neutralized powder)

    • Allows direct substitution incommercial formulations
    • Aqueous & organic coating
       

     

    Kollicoat® MAE 100 P
    (pre-neutralized powder)

    • No neutralization required
    • Suitable for extreme weather (powder)
    • Aqueous coating
       

     

    Kollicoat® MAE 30 DP
    (dispersion 30%)

    • Most efficient and cost-effective (not spray-dried)
    • Aqueous coating
    • Not suitable for freezing climate

     

    No more dusting thanks to unique powder particle shape

    The dry powder particles of Kollicoat® MAE 100-55 are larger and thus significantly less dusty than comparable 100-55 coating grades – much easier to work with for your operators:

    Equivalent drug release

    Despite its advantages in handling, Kollicoat® MAE 100-55 provides equivalent drug release as existing comparable coating grades in the market. And this means you can directly introduce it into your commercialized formulations.

    Coated Bupropion HCl tablets (150mg);
    N = 3; 50 rpm;
    Buffer change after 2 h;
    880ml HCl + 20 ml Tri-K phosphate

    Quality and regulatory status

    Kollicoat® MAE 100-55 is produced in Germany under GMP conditions. It complies to respective Ph.Eur., USP-NF, and JPE monographs:

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