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    Kolliphor® P188

      Flexible excipient to overcome a wide range of pharmaceutical challenges that provide formulators with increased efficiency and added functionality.

      Kolliphor® P 188 is an poloxamer that enables and enhances a wide range of functional applications. For instant and modified release applications, Kolliphor® P 188 can act as a stabilizer in oral suspensions. In formulations that include poorly soluble actives, Kolliphor® P 188 can improve solubility, absorption and bioavailability. Corresponding dosage forms can then be processed by melting or granulation. Kolliphor® P 188 serves as a plasticizing agent, a solubilizer and an emulsifier, supporting both solid and liquid dispersions, as well as emulsions and micro-emulsions. Kolliphor® P 188 can also act as a co-emulsifier in creams and emulsions for skin delivery applications.

      Kolliphor® P 188 can be used as an emulsifier and solubilizer, as a dispersing and wetting agent for solid dispersions and also to improve solubility, absorption and bioavailability of poorly soluble actives. It also is utilized as a co-emulsifier in creams, emulsions and as a suspension stabilizer and tablet lubricant. As dissolution enhancer, lubricant and wetting agent it is particularly suitable for wet granulation.

    Our Kolliphor® Portfolio
    BASF’s unparalleled portfolio of solubilizers and emulsifiers for topical products offers you the perfect solution, whatever the application or formulation type
    Our innovations include new solubilizers that enhance bioavailability of active ingredients
    The high performance and safety of BASF products is backed by comprehensive documentation – so you know you can rely on us
    Our flexible Kolliphor® solutions can be used for hot-melt and spray-drying processes
    BASF Poloxamers offer better solubilizing properties compared to HPMC, PVP and cyclodextrins. Also, our Poloxamers are non-ionic and less irritating

      Learn more about Kolliphor® P 188

    Application Guide

    Solubility Enhancement with BASF Pharma Polymers - Solubilizer Compendium

    Application Guide

    Hot Melt Extrusion with BASF Pharma Polymers - Extrusion Compendium, 2nd Revised and Enlarged Edition

    Kolliphor® P 188 Bio

    High purity poloxamer designed to reduce shear stress during biologics manufacturing


    Trends and Formulation Strategies for Topical Drugs

    Product Overview

    Focusing on your needs with platform solutions

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