Kolliphor® PS 60 is used as an emulsifier or co-emulsifier in topical pharmaceutical applications like creams and lotions and as non-ionic solubilizer in solid, semi-solid and liquid dosage forms or as foam stabilizer
Kolliphor® PS 60
Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. They are non-ionic surfactants and emulsifiers derived from polyethoxylated sorbitan and stearic or oleic acid. Polysorbates are mainly used as a solubilizer, emulsifier or suspension stabilizer for pharmaceutical application.
The choice of emulsifiers for specific applications depends on the desired properties of the formulation (i.e. stability, viscosity, skin feel and API), or on the desired processing technology (i.e. PIT, hot or cold processing).
Processing at room temperature to save time and energy
Besides the well known emulsifying process with two hot phases there is also the possibility to formulate an emulsion with a processing temperature at room temperature. The processing of O/W emulsions at room temperature has several significant benefits. For example, it is no longer necessary to heat the water and oil phase to 70-80 °C. This saves considerable amounts of energy and reduces the production time as the cooling step is eliminated. Another very important advantage is that head-sensitive APIs can be added to the emulsion at any point. Kolliphor® PS 60 is very suitable for this kind of application.