As water-soluble derivative of natural-source vitamin E, Kolliphor® TPGS is suitable for both oral and topical dosage forms with exceptional quality and high stability.
Kolliphor® TPGS solubilizes poorly soluble APIs and can directly enhance their bioavailability, increases permeability, and prevents actives from crystallization in spray crystallization. Plus, it is particularly suitable for use in combination with matrix formers or matrices. It can be used as an absorption enhancer, emulsifier, vehicle for lipid-based drug delivery, source of natural vitamin E, and antioxidant. It is commonly used in pharmaceutical and nutritional formulations, but also in cosmetics. Additionally it has plasticizing effects that are very beneficial for emerging platform technologies in the pharmaceutical industry such as hot melt extrusion (HME). Based on natural vitamin E manufactured by BASF, Kolliphor® TPGS is produced to the highest quality standards.