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    Kollisolv® PEG 400

    Excellent solvents for a large number of substances that do not readily dissolve in water

    The low-molecular weight liquid polyethylene glycol Kollisolv® PEG 400 is an excellent solvent for a large number of substances that do not readily dissolve in water. They are therefore widely used as solvents and solubilising agents for active substances and excipients in liquid and semi-solid preparations. It is the ability of PEGs to form complexes with active substances that is responsible for their excellent solvent power. However, equilibrium constants for complex formation vary considerably from one substance to another, and certain drugs such as Penicillin G and Bacitracin can even become inactivated. The effect of the polyethylene glycol on the efficacy and absorbtion of a drug must therefore always be determined in tests. With regard to incompatible substances, please see the remarks in the European Pharmacopoeia, Vol. II/3, Monographs M1, Macrogol 300, p. 3. Polyethylene glycols can also be used to adjust the viscosity of liquid pharmaceutical preparations and ointments, to modify their absorption properties and to stabilise the preparation.

    Technical Information

    Kollisolv® PEG Grades - Technical Information

    Liquid polyethylene glycols for the pharmaceutical industry

    Application Guide

    Hot Melt Extrusion with BASF Pharma Polymers - Compendium, 2nd and Enlarged Edition

    The compendium now provides readers with an even better understanding of solid dispersions and the hot-melt extrusion process, and offers even more real-world application data.

    Product Overview

    Focusing on your needs with platform solutions

    This brochure presents an overview of our leading-edge products, grouped in the following platforms: Instant and Modified Release, Solubilization, Skin Delivery and Softgels.