BASF offers an extensive portfolio of excipients for topical formulations enabling you to create the ideal skin delivery solution for ointment formulation. We are committed to maintaining the highest level of quality. Our range of solubilizers and penetration enhancers support effective delivery of the target API – the number-one priority when designing any dermatological product.
Ointments are single phase, hydrophilic or hydrophobic systems with sufficient consistency to allow the formulator to stably and homogeneously suspend dissolved or dispersed APIs. Hydrophilic ointments have the advantage of being less greasy or oily during and after application and they are easily washed off of skin after use. They also provide an excellent vehicle for the topical delivery of hydrophilic drugs.
The biggest challenges for formulators of hydrophilic ointments are ensuring that APIs remain solubilized or in a specific habit or polymorphic state throughout the life of the product, preventing the separation of fluid from the formulation (i.e. weeping) and ensuring that the formulation has acceptable spreadability on the skin. These challenges are overcome by the proper blending of compatible fluids and solvents with higher melting point solids.
BASF offers functional excipients to meet these needs.