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    Create the ideal solution for your foam formulation

    Our skin delivery solutions


    Pharmaceutical Foams

    BASF offers wide range of excipients for topical formulations enabling you to create the ideal skin delivery solution for your foam formulation. 

    By extensively analyzing, refining and enhancing the sensorial effects of each ingredient class, we can help you to create products that increase patient compliance. We are committed to maintaining the highest level of quality. At the same time, we have focused on improving the mildness of formulations. Our range of solubilizers support effective delivery of the target API – the number-one priority when designing any dermatological product.

    Topical foams are growing in importance in the topical dermatological field. These can take the form of aerosol foams with a dense, creamy consistency (e.g. mousse) or non-aerosol pump foams with a looser, less dense consistency. There are numerous advantages associated with foams: (1) They allow for the clean, targeted application of APIs that must be delivered from a liquid. (2) In aerosol systems all of the ingredients are typically completely solubilized in the primary package, thereby circumventing issues of physical stability that are associated with other dosage forms. (3) Foams can be a superior choice for vaginal or rectal applications.

    Benefits
    Extensive expertise and understanding of topical products
    High quality consistency factors for improved stability and optimized sensory performance
    Broad range of solubilizers for effective delivery of your target API
    Meets the highest regulatory and quality requirements

    Some of the key functional excipients that BASF offers for foam formulations include:

    Emulsifiers

    The air-water interface of foam cells (bubbles) is stabilized by emulsifiers. For aerosol foams any of our Kolliphor® series may be considered. For non-aerosol aqueous foams our Kolliphor® P series (poloxamers) are a superior choice.

    Consistency factors

    Fatty alcohols (e.g. Kolliwax® SA, Kolliwax® CA or Kolliwax® CSA 50) can be used to both increase the stability of foam lamellae (the thin film of liquid between bubbles) and optimize the sensory properties.

    Solvents

    Prior to extrusion as a foam APIs must be dissolved in the formulation. Our Kollisolv® and Kolliphor® products, as well as low molecular weight polyvinylpyrrolidones (Kollidon® 12, Kollidon® 17, Kollidon® 25 and Kollidon® 30) are all excellent options to consider as solubilizers.

    Product Overview

    Focusing on your needs with platform solutions

    This brochure also features BASF's functional solutions for foams.

    Poster

    Foam Formulations

    The foaming capability and properties of four topical aerosol foam formulations were evaluated.

    Under The Microscope

    The Relationship Between Critical Quality Attributes and the Microstructure

    The performance and efficacy of topical semi-solid drug products are determined by the different microstructures that are the result of mixing and organizing excipients and APIs.