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    Excipients for Drug Formulation Skin Delivery Platform


    Skin Delivery

    The perfect solution for every skincare challenge

    BASF offers an unparalleled portfolio of excipients for topical formulations, enabling customers to create the ideal skin delivery solution for each and every application. We are committed to maintaining the highest level of quality across the product spectrum. Our range of solubilizers and penetration enhancers supports effective delivery of the target API, which is a key priority when designing any dermatological product. At the same time, we have focused on improving the mildness of formulations. And by extensively analyzing, refining, and enhancing the sensorial effects of each ingredient class, we can help our customers create products that increase patient compliance. In addition, BASF works closely with leading global organizations on the design, evaluation and microstructure of semi-solid formulations.

    Experience and expertise
    BASF is the global market leader in dermatological ingredients. Our premium solutions are based on 150 years of industry experience in oleochemistry.

    GMP production and regulatory support
    BASF's pharmaceutical-grade dermatology products satisfy all the relevant regulatory requirements. Our integrated quality management is certified in line with the highest quality standards – providing you with products you can trust.

    Tailored customer service
    Our in-depth expertise and understanding of the dermatology industry enables us to offer tailored solutions and customized excipients if required.

    Benefits
    Key industry partner, with a broad dermatological ingredients portfolio
    Extensive expertise and understanding of topical products
    Innovative breakthroughs such as improved delivery systems
    Meets the highest regulatory and quality requirements

    Skin Delivery Applications

    In Focus

    Topical Drug Formulation Tips and Techniques

    Read about current trends, skin delivery solutions and formulation strategies.

    In Focus

    Microstructure in topical drug development

    Learn more about the importance of microstructure in topical drug development and how BASF is playing an integral role in this hot industry topic.

    Product Overview

    Focusing on your needs with platform solutions

    Webcast

    Excipient Selection to Enable the Performance of Skin Delivery Dosage Forms

    Webcast

    Understanding the Relationship Between Critical Quality Attributes and the Microstructure of Topical Semi-Solid Formulations.

    Webcast

    Thermal sintering for  controlled drug release of hydrophilic drugs

    Webcast

    BASF Pharma Solutions for Dermal Drug Delivery

    ebook

    Trends and Formulation Strategies for Topical Drugs

    ebook

    Optimizing Topical Semi-Solid Drug Formulation and Performance

    Whitepaper

    The Relationship Between Critical Quality Attributes and the Microstructure of Topical Semi-Solid Formulations

    Whitepaper

    Controlling the physical properties and performance of semi-solid formulations

    One Pager

    Foam Formulations

    One Pager

    Poloxamers as Gelling Agents in Topical Formulations

    The Medicine Maker

    Micro-Formulating for Dermal Drug Delivery

    Pharmtech

    Optimizing Semisolid Dosage Forms

    Pharmaceutical Technology

    Topical Formulation: Moving From Art to Science

    Pharma's Almanac

    https://www.pharmasalmanac.com/articles/topical-drug-formulations-strong-growth-based-on-new-understandings

    AAPS PharmSciTech

    Design and Evaluation of Topical Diclofenac Sodium Gel Using HME Technology as a Continuous Manufacturing Process

    Video

    Understanding the Role of Excipients in Topical Semi-Solid Microstructure and Critical Performance Parameters

    Podcast

    The role of semisolid microstructure in topical formulation performance and functionality

    Video

    The Importance of Microstructure in Topical Drug Product Development

    Podcast

    Characterizing Microstructural Differences of Semisolid Topical Dosage Forms

    Download Center

    Looking for application guides, technical and scientific posters, brochures or technical information? Visit our download center.

    overview

    Skin Delivery Videos

    Introduction to BASF Skin Delivery Platform

    An understanding of excipient behavior both in providing a stable formulation and supporting topical drug delivery is the first element of effective skin-delivery formulation design. In this video, Dr. Amy Ethier demonstrates how the BASF Pharma Solutions lab in Tarrytown, NY, can be a robust resource in your skin-delivery formulation efforts.
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    Introduction to BASF Skin Delivery Platform

    An understanding of excipient behavior both in providing a stable formulation and supporting topical drug delivery is the first element of effective skin-delivery formulation design. In this video, Dr. Amy Ethier demonstrates how the BASF Pharma Solutions lab in Tarrytown, NY, can be a robust resource in your skin-delivery formulation efforts.
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    Formulating Foams

    BASF expert Amy Ethier explains how formulation components impact an aerosol and non-aerosol pharmaceutical foam formulation and the sensory properties of the finished product.
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    Formulating Anhydrous Dosage Forms

    BASF expert Amy Ethier explains how one can formulate an ointment with a lipophilic, water-sensitive active pharmaceutical ingredient (API).
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    Formulating Ointments

    BASF expert Amy Ethier explains how taking advantage of the tunability and solubilization properties of polyethylene glycol (PEG) can result in a pharmaceutical ointment with improved sensory properties over petrolatum-based alternatives.
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    Formulating Poloxamer Gels

    BASF expert Amy Ethier explains how one can achieve the unique sensory properties of this increasingly popular pharmaceutical dosage form using both hot and cold process methods.
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    Formulation Trends for Topical Dosage Forms

    A deep dive into an important issue: How do you leverage excipient functionalities to achieve a variety of important product performance attributes? In this video series of ten clips recorded at CPhI North America 2017, we discuss current Formulation Trends for Topical Dosage Forms with Pharmaceutical Technology!
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    The four pillars of Skin Delivery

    The four pillars of Skin Delivery are a result of continuous conversation with the marketplace and our customers: Dermal drug delivery, Mildness, Sensory and Formulation Design. Learn more on why each pillar is crucial and plays an important role for Skin Delivery.
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    Sensory Quality and Excipients Choice

    Formulators usually face three kinds of challenges while addressing sensory quality. Firstly, when existing products are changed, the sensory properties should feel the same for customers and patients. In addition to that, sensory problems like formulations that are too greasy, sticky or contain other negative feelings must be tackled. Lastly, you should send positive and beneficial sensory messages to the patients while designing the formulation. “With the right pallet of excipients, you can create different feelings. It’s a bit like Art”; says Norman Richardson, Global Technical Development & Marketing Skin Delivery at BASF Pharma. Formulators usually face three kinds of challenges while addressing sensory quality. Firstly, when existing products are changed, the sensory properties should feel the same for customers and patients. In addition to that, sensory problems like formulations that are too greasy, sticky or contain other negative feelings must be tackled. Lastly, you should send positive and beneficial sensory messages to the patients while designing the formulation. “With the right pallet of excipients, you can create different feelings. It’s a bit like Art”; says Norman Richardson, Global Technical Development & Marketing Skin Delivery at BASF Pharma.
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    Addressing Challenges with Cremes

    Amy Ethier, Skin Delivery Formulation Scientist at BASF Pharma, sits down with Pharmaceutical Technology at CPhI North America 2017. How to address challenges with cremes? Why should formulators especially consider the excipients being used in creme development? And what does the ideal creme formulation look like?
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    Special Considerations for Gels

    One Gel is not necessarily like another – it highly depends on the customer or region. For example, harder climate makes light formulation with Gels very popular in the Asia/Pacific region. Or take the US, where emphasis on Transdermal Gels is growing - this video gives an overview on the special considerations for Gels.
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    The right Excipient Selection for Foams

    With air as another phase, foams have their unique set of challenges – but also offer opportunities. Learn why looking at the end-formulation and considering interactions is crucial for the right selection of excipients.
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