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    Functional solutions for formulations with sustained drug release

    Sustained release profiles allow tailored dosing of the active ingredient over an extended period of time up to 24 hours. Common ways to achieve such release rates are the use of film coating, a sustained release matrix or sustained release drug-loaded granules. BASF offers powerful excipients that provide almost endless design space for sustained release formulations.

    One of the major challenges for marketers of pharmaceutical products is the compliance of the patient. When a drug needs to be adminstered several times a day, patients acceptance of the medication can decrease considerably, leaving the risk of insufficient treatment. A common solution to increase medication acceptance in this case is to formulate the drug in a dosage form that releases the active ingredient steadily over an extended period of time. Such sustained release formulations have gained considerable traction in the pharmaceutical industry, and will continue to be a major tool to improve the patients experience for existing and new drugs. It also represents an attractive opportunity for companies and formulators in particular to differentiate their potentially generic product from standard instant release versions in the market. We offer a distinct set of highly functional materials that allow you to flexibly design your desired sustained release profiles.

    Sustained release solutions
    Increased patient compliance
    Differentation of your dosage form
    in the market
    Efficient processing, reducing ecological
    footprint

    Sustained release formulations meeting the ADD regulations

    Modified release dosage forms are helpful for patients, as they provide pharmacological advantages and administration convenience. However, dose dumping, which is defined as the rapid release of a large portion or the entire dose, is of growing concern. This is often the consequence of the consumption of alcoholic beverages (so-called alcohol induced dose dumping, ADD). This is of particular concern as it may unintentional put the patient at significant health risks. Regulatory bodies worldwide have lately adapted regulations in order to avoid the risk of such accidental dose dumping.

    Brochure

    Ensuring the precision you need – every time

    Selected key formulation challenges in Instant & Modified Release dosage forms solved with functional excipients from BASF.

    Product Overview

    Focusing on your needs with platform solutions - Product Overview 2017

    This brochure presents an overview of our leading-edge products, grouped in the following platforms: Instant and Modified Release, Solubilization, Skin Delivery, Softgels, and Biologics Solutions

    Learn more with our webinars, articles and posters

    ebook

    Overcoming Challenges in Sustained-Release Drug Formulation

    Webinar (on demand)

    Product innovation on modified release coatings (sustained release and enteric coatings)

    Webinar (on demand)

    Sustained-Release Formulation: Overcoming Key Challenges Like Alcohol-Induced Dose Dumping

    Webinar (on demand)

    Thermal Sintering for  Controlled Drug Release of Hydrophilic Drugs

    Learning Tool

    Overcoming Challenges in Sustained-Release Drug Formulation

    Poster

    Alcohol-Induced Dose Dumping Resistant Matrix Tablets with Kollidon® SR

    Poster

    A Kollicoat® SR 30D/Kollicoat® MAE 30DP Coating System for Delayed Modified Drug Release

    American Pharmaceutical Review

    Controlled release: a new paradigm with polyvinyl acetate polymer

    Download Center

    Looking for application guides, technical and scientific posters, brochures or technical Information? Visit our Download Center.

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