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    Excipients for Drug Formulation Topical Polymeric Films


    Topical Polymeric Films

    BASF offers a number of film formers and plasticizers for topical formulations enabling you to create the ideal skin delivery solution for your topical polymeric film formulation.

    Topical dermatological formulations that form intact films on the skin surface, after application, have several possible advantages: (1) They can hold APIs on the skin surface at the site of efficacy for longer periods of time by resisting rub off or wash off, (2) They can provided added protection to the skin by providing a physical barrier to dirt, microorganisms, toxins, etc. (3) They can create a reservoir on the surface of the skin, from which API is released in a controlled fashion. (4) They can prevent the transfer of excipients and APIs from the skin surface to clothing, other people, pets, etc.

    Functional excipients for topical polymeric films include:

    Film formers

    Our Kollicoat® and Kollidon® products offer a variety of different chemistries which form films with varying degrees of retention and solubility. Topical films can then be designed which are resistant to washing or alternatively, which may be easily washed off.

    Plasticizers

    In order for films to be able to flex, stretch and move with the skin after application, plasticization may be required. Our Kollisolv® GTA (triacetin), Kollisolv® PEG 300 or Kollisolv® PEG 400, Kollisolv® PG (propylene glycol) and Kolliphor® P124 (poloxamer 124) are all exceptional options.

    Benefits
    Robust portfolio of polymeric film formers to meet a variety of needs
    Variety of exceptional plasticizers
    Extensive expertise and understanding of topical products
    Meets the highest regulatory and quality requirements

    Brochure

    Focusing on your needs with platform solutions

    This brochure also features BASF's functional solutions for topical polymeric films.