Global
APIs & Raw Materials

Raw Materials for the Pharmaceutical Industry

BASF offers the world's largest portfolio and  variety of chemical raw materials to meet the specific needs of your API production. 

Leading supplier of omega-3 and ibuprofen

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BASF is the world leading manufacturer of active pharmaceutical ingredients (APIs) such as ibuprofen and omega-3 fatty acids. BASF has focussed on the production of a small selected active pharmaceutical ingredients. Our portfolio also includes APIs such as Polyethylene Glycol 3350 (Macrogol/PEG) and L-Menthol. With a strong international presence, BASF is a truly global partner that can also offer reliable local support. And thanks to our state-of-the-art production facilities located around the world, we can deliver the products you need – wherever and whenever you need them.

BASF Intermediates develops, produces and markets the world’s largest portfolio of chemical intermediates products. This portfolio of more than 700 products comprises top quality, Building Blocks, Chiral Auxiliaries, Protective Groups, Reagents and Solvents for chemical synthesis in the pharmaceutical industry.

Your Benefits

  • High product quality
  • Seamless production capability up to commercial scale
  • Stable supply with a global network
  • Regulatory documents support
  • Customized solutions
raw materials for the pharmaceutical industry

Excipients for Drug Formulation

Equipped with an in-depth understanding of multiple industries, technologies and applications, we have the skills and resources to make drug manufacturing more efficient, robust, and cost-effective. Whether you want to make your medicine more effective, safer, or more patient-friendly, BASF has the solution you need. Find the right answers to your pharmaceutical formulation challenges.

Our Portfolio

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Building Blocks 

BASF’s innovative technology platform and our extensive expertise in biocatalysis enable us to manufacture a wide range of building blocks. Our offerings include a large number of chiral intermediates and non-chiral specialties e.g. heterocycles and acid chlorides.
Leistungsfähige Katalysatoren sind für die Produktionsverfahren in der chemischen Industrie von entscheidender Bedeutung, sowohl aus ökonomischen als auch aus ökologischen Gründen. Mehr als 85 Prozent aller Produkte der BASF werden mit Hilfe von Katalysatoren hergestellt, wobei die heterogene Katalyse mit einem Feststoff als Katalysator im Vordergrund steht. Die Katalysatoren werden individuell an die Erfordernisse der verschiedenen Prozesse angepasst, was in der Katalyseforschung ein stark interdisziplinäres Arbeiten verlangt. Bei der BASF sind derzeit etwa 250 verschiedene Katalysatoren im Sortiment. Sie werden zunächst in den eigenen Produktionsanlagen eingesetzt und wenn sie sich bewähren, auch auf dem freien Markt angeboten.From both economical and environmental viewpoints, effective catalysts are of vital importance for the production processes used in the chemical industry. More than 85 percent of BASF products are produced with the aid of catalysts. The focus is on heterogeneous catalysis that utilizes catalyst present in a solid form. Since catalysts are adapted individually to the needs of various processes, close interdisciplinary collaboration is required in catalysis research. Currently, about 250 different catalysts are available in the BASF range. These catalysts are initially used at BASF's own plants and once proven are sold on the free market.

Catalysts

The Catalysts-portfolio includes fine-chemical-catalysts and a full loop of metals-management-services. With its human nutrition solutions, BASF offers a broad portfolio for consumers’ needs, including vitamins, carotenoids, plant-sterols, emulsifiers and omega-3.
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Chiral Auxiliaries

Our customers benefit from the availability at commercial scale of chiral amines, alcohols, epoxides and acids that are marketed under the ChiPros® trademark and prepared using BASF’s robust technology platforms. 
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Protective Groups

In numerous complex synthesis routes for APIs, some functional groups have to be shielded against conversion in a specific reaction step. For this purpose, BASF offers a range of compounds that provide the necessary protection in your transformations. Various types of functions ranging from alcohols to amines can be protected.
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Reagents

BASF’s portfolio includes organic reagents and inorganic specialty reagents, various boranes and specialty bases that facilitate reactions with high selectivity. To support your development work from lab to launch, all reagents are available in quantities from kilograms to tons.
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Solvents 

BASF produces solvents of highest quality that meet the specific needs of the pharmaceutical industry. We also offer comprehensive packages of support services and newly developed solutions for selected products.

Extensive technology platform

BASF has one of the most extensive technology platforms for manufacturing specialties for the pharmaceutical industry. These include technologies for chiral as well as achiral intermediates. The technology portfolio spans the whole range from classical to modern technologies like phosgene chemistry and enantioselective biotransformations.
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Unparalleled dedication to quality

BASF's quality system also includes the following processes and procedures:

■      Procedure for handling changes
■      Non-conformance management (NCM) system
■      Suitable buildings, facilities & hi-tech process equipment
■      Process control during production

All products of the lntermediates division are manufactured under ISO 9001 conditions. The Quality System of BASF's lntermediates division is based on the following:

■        ISO 9001: 2015 or comparable QM system
■        Quality, safety, health & environment - (QSHE) policy
■        Documented procedures

The Quality System of the lntermediates division is certified according to the international DIN ISO 9001:2015 standard or comparable quality management system.