Suppositories

A medium spreading emollient and solubilizer for lipophilic APIs.

A fast spreading emollient with broad penetration enhancement properties for lipophilic APIs.

A medium spreading emollient with penetration enhancement properties, and a potential solvent for lipophilic solvents.

A medium spreading non-ester emollient which is stable against acid and base hydrolysis and provides good skin penetration.

The Kollidon^® CL family is the industry’s widest portfolio of super-disintegrants and dissolution enhancers. These highly functional cross-linked PVP polymers ensure that active ingredients are released from any solid dosage form at exceptionally high speed. In addition, they improve bioavailability of certain poorly soluble APIs.

Kollidon^® VA64 is used in granulation and as a dry binder in tablets, capsules and granules, as a film-forming agent in tablet coatings and subcoatings, and as a film-forming agent in topical sprays. Soluble copovidone widely used for instant release formulation and is suitable in hot-melt extrusion processes.

A self-emulsifying mixture of emulsifier and consistency factors for simplified preparation of skin cream base.

Kolliphor^® ELP is a non-ionic oil-in-water emulsifier and/or solubilizer for sensitive active ingredients

A potent nonionic solubilizer

A polymeric multi-talent suitable for a large variety of applications, i.e. Kolliphor^® P 338 can be used as solubilizer, emulsifier and plasticizer.

Kolliphor^® PS 20 is a non-ionic, hydrophilic emulsifier, co-emulsifier and solubilizer for pharmaceutical preparations like emulsions and creams, gels and foams as well as softgels.

Kolliphor^® PS 60 is used as an emulsifier or co-emulsifier in topical pharmaceutical applications like creams and lotions and as non-ionic solubilizer in solid, semi-solid and liquid dosage forms or as foam stabilizer.

Kolliphor^® PS 80 is a non-ionic, hydrophilic emulsifier, co-emulsifier and solubilizer for pharmaceutical preparations like like emulsions and creams, gels and foams as well as softgels.

Medium chain triglyceride compatible with fat-soluble vitamins, actives and essential oils

Excellent solvents for a large number of substances that do not readily dissolve in water

Excellent solvents for a large number of substances that do not readily dissolve in water

A high molecular polyethylene glycol (macrogol) mainly used as solvent for oral, topical and parenteral preparations.

Manufactured under cGMP, Kollisolv® PG (1,2-propyleneglycol) can used across a wide range of applications, i.e. as plasticizer, solvent or co-solvent, stabilizer, or as carrier for emulsifiers.

A commonly used fatty alcohol, consistency factor.

A fatty alcohol mixture, preferred for its stability in emulsion formulations.

A fatty alcohol mixture, preferred for its stability in emulsion formulations.

An O/W co-emulsifier and consistency factor with low melting point and soft sensory effect.

As lipophilic lubricant Kolliwax^® SA is the first choice for sensitive acidic APIs. It is commonly also used as viscosity regulator for oil-in-water emulsions and as a pH independent sustained release agent. Kolliwax^® SA acts as a plasticizer with included consistency factor in solid dispersions. It hardens suppository formulations and adjust their melting points.

Kolliwax^® S Fine can be used for various oral solid as well as semi-solid dosage forms: It can be used as a lubricant in oral dosage forms, matrix forming agent in sustained-release dosage forms, emulsifying and solubilizing agent in topical formulations and hardening agent in glycerin suppositories. Kolliwax^® S Fine is particularly suitable for sensitive APIs.

The best option for suppository masses or solid compositions.