Excipients for Drug Formulation

Suppositories: Matrix builders

BASF offers a variety of hard fats, waxy solids, PEGs and poloxamers ideal for use as matrix builder and structurants in suppository formulations.

Matrix builders are the materials that create the solid state that gives the suppository the solidity that allows it to be handled prior to application. Depending on the type of suppository, matrix builders can be added to fluid oils or water, in order to build up the hardness. BASF offers numerous materials to make oil-based or water-based suppositories.


  • Variety of hard fats, waxy solids, PEGs and poloxamers ideal for use as matrix builder in suppositories
  • Extensive expertise and understanding of topical products
  • Meets the highest regulatory and quality requirements

Hard fats

Hard fats are pre-blended fatty solids that can melt within a specific temperature range that may be found in the rectum, colon or vagina. Our Novata® products offer a variety of typical melting point ranges.


Poloxamers have been explored as stiffening agents in suppositories but have not yet been approved in a marketed product. BASF offers Kolliphor® P188 and Kolliphor® P407 for your product development exploration.

Learn more about our matrix builder solutions for suppository masses

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