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Excipients for Drug Formulation
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Excipients for Drug Formulation
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Global
Excipients for Drug Formulation

Create the ideal skin delivery
solution for your topical
polymeric film formulation

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Global
Excipients for Drug Formulation

Topical Polymeric Films

BASF offers a number of film formers and plasticizers for topical formulations enabling you to create the ideal skin delivery solution for your topical polymeric film formulation.

Topical dermatological formulations that form intact films on the skin surface, after application, have several possible advantages: (1) They can hold APIs on the skin surface at the site of efficacy for longer periods of time by resisting rub off or wash off, (2) They can provided added protection to the skin by providing a physical barrier to dirt, microorganisms, toxins, etc. (3) They can create a reservoir on the surface of the skin, from which API is released in a controlled fashion. (4) They can prevent the transfer of excipients and APIs from the skin surface to clothing, other people, pets, etc.

Benefits

  • Robust portfolio of polymeric film formers to meet a variety of needs
  • Variety of exceptional plasticizers
  • Extensive expertise and understanding of topical products
  • Meets the highest regulatory and quality requirements

Functional excipients for topical polymeric films include:

Film formers

Our Kollicoat® and Kollidon® products offer a variety of different chemistries which form films with varying degrees of retention and solubility. Topical films can then be designed which are resistant to washing or alternatively, which may be easily washed off.

Plasticizers

In order for films to be able to flex, stretch and move with the skin after application, plasticization may be required. Our Kollisolv® GTA (triacetin), Kollisolv® PEG 300 or Kollisolv® PEG 400, Kollisolv® PG (propylene glycol) and Kollisolv® P124 (poloxamer 124) are all exceptional options.

Learn more about our solutions for topical polymeric films

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Discover our portfolio of functional excipients for your topical polymeric film formulation

Kollicoat® IR

As instant release film former, Kollicoat® IR combines exceptional coating quality with simple, robust processing. As wet binder, it combines powerful binding with no peroxides at all. And all those characteristics also make it a great pore former for sustained release formulations.

Kollicoat® SR 30 D

Precise, pH-independent sustained release for multiple applications

Kollidon® 30

Our medium-molecular povidone is used in endless ways in pharmaceutical formulations - as binder, pore former, stabilizer, thickener, as solubilizing agent, crystallization inhibitor and many more. And with our trusted quality, it will always serve exactly what you intended it for.

Kollidon® 90 F

A highly effective binder, for use as a stabilizer in oral and topical suspensions, as a thickener, and as a hydrophilizing agent or pore-forming agent in medical plastics.

Kollidon® SR

Direct Compression Sustained Release

Kollidon® VA64

Kollidon® VA64 is used in granulation and as a dry binder in tablets, capsules and granules, as a film-forming agent in tablet coatings and subcoatings, and as a film-forming agent in topical sprays. Soluble copovidone widely used for instant release formulation and is suitable in hot-melt extrusion processes.

Kolliphor® ELP

Kolliphor® ELP is a non-ionic oil-in-water emulsifier and/or solubilizer for sensitive active ingredients

Kolliphor® HS 15

A potent nonionic solubilizer

Kolliphor® P188

Flexible excipient to overcome a wide range of pharmaceutical challenges that provide formulators with increased efficiency and added functionality.

Kolliphor® PS 20

Kolliphor® PS 20 is a non-ionic, hydrophilic emulsifier, co-emulsifier and solubilizer for pharmaceutical preparations like emulsions and creams, gels and foams as well as softgels.

Kollisolv® GTA

A hydrophilic plasticizer used in both, aqueous and solvent-based polymeric coating of capsules, tablets and granules. Also used as a solubilizer and solvent as well as a humectant.

Kollisolv® P 124

The only monographed poloxamer that is liquid at room temperature – making it ideal for liquid dosage forms. It is used for liquid-filled softgel capsules as a dispersion medium for APIs, or as plasticizer for tablet formulations.

Kollisolv® PEG 300

Excellent solvents for a large number of substances that do not readily dissolve in water

Kollisolv® PEG 400

Excellent solvents for a large number of substances that do not readily dissolve in water

Kollisolv® PG

Manufactured under cGMP, Kollisolv® PG (1,2-propyleneglycol) can used across a wide range of applications, i.e. as plasticizer, solvent or co-solvent, stabilizer, or as carrier for emulsifiers.

Novata®

The best option for suppository masses or solid compositions.

Soluplus®

With its excellent capability to form solid solutions, Soluplus® is suitable for innovative processing technologies, such as hot melt extrusion. Soluplus® was awarded with the CPhI Silver Innovation Award in 2010.

Discover BASF's functional solutions for your topical polymeric film formulation

Film forming

BASF has a robust portfolio of polymeric film formers to meet a variety of needs.

Plasticizers

BASF offers a selection of plasticizers suitable for topical polymeric films

Related Solution Platforms

Skin Delivery Platform

The perfect solution for every skincare challenge.

Instant & Modified Release Platform

BASFs rich portfolio of instant and modified release solutions offers an unprecedented range of functionality.