Global
Excipients for Drug Formulation

Kollicoat® MAE 30 DP

The reliable and safe enteric coating for solid oral dosage forms

Kollicoat® MAE 30 DP is reliable, high-performance film coating based on methacrylic aid-ethyl acrylate copolymer (1:1), designed specifically for enteric tablet coating. Many APIs degrade in the acidic environment of the stomach or irritate its lining. But the smart polymers in Kollicoat® MAE shield active ingredients from aggressive gastric juice and only dissolve once in the intestine – making sure the API is released in precisely the right place. Kollicoat® MAE 30 DP is an aqueous dispersion with a solids content of 30 percent. This product offers robust protection, while facilitating more simple and cost-effective production processes.

Why choose Kollicoat® MAE?

  • Reliable, high-performance enteric coating
  • Excellent resistance to gastric juices
  • Rapid release at pH values greater than 5.5
  • Easy and efficient processing

Application examples

Protection of gastro-sensitive active
ingredients

 

Protection of gastric mucosa from aggressive actives

 

Gastrointestinal targeting

e.g. proton-pump inhibitors, enzymes, peptides, antibiotics

e.g. COX-1-inhibitors, iron compounds, acetylsalicylic acid, diclofenac-sodium

e.g. budesonide, clarithromycin, doxazosin, pancreatic enzymes

Product Details
Applications: The main application is as film-former in enteric coatings for solid dosage forms
Trivial Names: Methacrylic Acid Copolymer Type C (USP), Methacrylic Acid Copolymer LD (JPE) and Methacrylic Acid-Ethyl Acrylate Copolymer (Ph. Eur.), Methacrylsäure Copolymer.
Description: The Kollicoat® MAE grades contain 0.7% sodium lauryl sulfate and 2.3% Polysorbate 80 as emulsifying agents. (The percentages refer to the solid substances.) The fatty acids used in the manufacture of Polysorbate 80 are of vegetable origin. The Kollicoat MAE grades are weakly acidic copolymers that dissolve at a pH above 5.5. 
Product Form: Kollicoat® MAE 30 DP is an aqueous dispersion with a solids content of 30%. The milky white, low-viscosity product has a faint, characteristic odour.
CAS-No: 25212-88-8
INCI: Acrylates Copolymer
Regulatory Status: Kollicoat® MAE 30 DP meets the requirements of the current monograph for Methacrylic Acid- Ethyl Acrylate Copolymer 1:1 Dispersion 30 Per Cent in Ph. Eur., Methacrylic Acid Copolymer Dispersion in USP/NF and Methacrylic Acid Copolymer LD in JPE.
Registrations Kollicoat® MAE 30DP:
  • Ph. Eur – Methacrylic acid – ethyl acrylate copolymer (1:1) dispersion (30 %) 
  • USP/NF – Methacrylic acid copolymer dispersion 
  • JP – Methacrylic acid copolymer LD 
  • IIG listing – Methacrylic Acid – Ethyl Acrylate Copolymer (1:1) Type A and Methacrylic Acid Copolymer Type C

Discover more about Kollicoat® MAE 30 DP

Portfolio Overview

Focusing on your needs with platform solutions

Download Center

Looking for application guides, technical and scientific posters, brochures or technical information? Visit our Download Center.

Related Functionalities

Related Process Technologies

Related Solution Platforms