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Excipients for Drug Formulation

Kollicream® DO

A medium spreading emollient and solubilizer for lipophilic APIs

Kollicream® DO provides good emolliency and moisture barrier properties in semi-solid creams and lotions, and is able to penetrate stratum corneum lipid domains. Due to its unsaturated C18 chain it can disrupt lipid ordering, thereby enhancing penetration of some APIs. It can also be used to aid in solubilization of some hydrophobic actives. Kollicream® DO can be used in emulsions & creams, ointments, gels and foams.

Our Kollicream® types can be used as emollient in creams and lotions. This high performance emollient offers incredible flexibility and efficiency for topical drug delivery systems, allowing you to adapt variables such as spreading value, molecular weight, or water permeability in line with your needs. With their moisture retention effect, fattening and re-fattening power, these topical excipients are able to care and protect the skin. Within the formulation they also have an impact on the consistency and appearance of the cream or lotion.

Why use Kollicream® DO

  • Good emolliency and moisture barrier properties in semi-solid creams and lotions
  • Able to penetrate stratum corneum lipid domains
  • It can disrupt lipid ordering, thereby enhancing skin penetration of some APIs
  • It is a potential solubilizer of lipophilic APIs
Product Details
CAS No.: 3687-46-5
Former Product Name: Cetion® V PH
Regulatory Status:

Complies with European Pharmacopoeia monograph and is manufactured under IPEC-PQG GMP conditions.

Ph. Eur.: Decyl oleate

Applications: Due to its medium spreading value, it can provide good emolliency and moisture barrier properties in semi-solid creams and lotions.

Learn more about Kollicream® DO

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