Kollidon® 12 PF
The endotoxin-controlled PVP-based solubilizers for parenteral and oral formulations
Kollidon® 12 PF and Kollidon® 17 PF, our soluble low molecular and pyrogen-free Kollidons, deliver functionality to many different areas of formulation.
They can be used to stabilize micro-molecular structures in injectables and lyophilisates. They can also form hydrogen bonds with compounds with complementary structures for improved dissolution. Kollidon® 12 PF serve as solubilizing agents and crystallization inhibitors particularly for injectables. These properties are of particular interest for antibiotics in solution or lyophylisate form. Kollidon® 12 PF are used in e. g. sulfonamide, melphalan, meclofenoxat, metroni- dazol, mistellectine, taurolidine and trimethoprim formulations. In the area of Instant & Modified release, Kollidon® 12 PF serve as pore former in solid oral dosage forms with sustained release, and allow viscosity enhancement in oral liquid & oral semi-solid dosage forms.
Did you know that Kollidon® 12 PF is highly suitable for injectable formulations?
- Highly soluble low molecular weight povidone
- Suitable as solubilizer and crystallization inhibitor
- PeroXeal™ packaging for minimizing peroxide formation
|Regulatory Status:||Kollidon® 12 PF meets the requirements of the current harmonised monographs for povidone in Ph. Eur. and USP-NF.|
- Solubilizing agent
- Crystallisation inhibitor
- Pore former in solid oral dosage forms
- Viscosity enhancement in oral liquid & oral semi-solid dosage forms
Learn more about Kollidon® 12 PF