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The endotoxin-controlled PVP-based solubilizers for parenteral and oral formulations
Kollidon® 12 PF and Kollidon® 17 PF, our soluble low molecular and pyrogen-free Kollidons, deliver functionality to many different areas of formulation.
They can be used to stabilize micro-molecular structures in injectables and lyophilisates. They can also form hydrogen bonds with compounds with complementary structures for improved dissolution. Kollidon® 12 PF serve as solubilizing agents and crystallization inhibitors particularly for injectables. These properties are of particular interest for antibiotics in solution or lyophylisate form. Kollidon® 12 PF are used in e. g. sulfonamide, melphalan, meclofenoxat, metroni- dazol, mistellectine, taurolidine and trimethoprim formulations. In the area of Instant & Modified release, Kollidon® 12 PF serve as pore former in solid oral dosage forms with sustained release, and allow viscosity enhancement in oral liquid & oral semi-solid dosage forms.
Product Details | |
Chemical name: | Polyvinylpyrrolidone |
CAS-No: | 9003-39-8 |
INCI: | PVP |
Regulatory Status: | Kollidon® 12 PF meets the requirements of the current harmonised monographs for povidone in Ph. Eur. and USP-NF. |
Applications
Learn more about Kollidon® 12 PF
PVP (Polyvinyl pyrrolidone) – An all-round talent with tradition
PVP has a long tradition at BASF and is one of the most interesting and versatile polymers used in the pharmaceutical industry.