Excipients for Drug Formulation

Kollidon® VA64

A copovidone used in granulation and as a dry binder in tablets, capsules and granules, as a film-forming agent in tablet coatings and subcoatings, and as a film-forming agent in topical sprays. Soluble copovidones are widely used for instant release formulation and is suitable in hot melt extrusion processes.

Kollidon® VA 64 is a vinylpyrrolidone-vinyl acetate copolymers. It is used as dry binder for direct compression tableting, as granulating agent, as retarding and as a film-forming agent as well as in taste-masking applications. As copovidone with an exceptionally high binding capacity, Kollidon® VA 64 can be used as a dry binder for direct compression tableting and as a soluble binder for granulation. These properties make it an attractive and cost-effective alternative to natural binders. In addition, it is ideal as a solubilizer in hot-melt extrusion processes. Kollidon® VA 64 is especially suitable for markets with higher humidity exposure.

Benefits of Kollidon® VA 64

  • The original PVP from the industry’s most experienced team
  • Especially suitable for direct compression, roller compaction, hot melt extrusion processes as well as for markets with high humidity exposure
  • Superior plasticity for very hard tablet production
  • Compliant with the current monographs for copovidone
  • Consistently high quality for reliable performance and formulation stability

Applications for Kollidon® VA64

Product Details
Chemical name: Vinylpyrrolidone-vinyl acetate copolymer
CAS-No: 25086-89-9
INCI: PVP/VA Copolymer
Regulatory Status: Kollidon® VA 64 meets current Ph. Eur., USP monograph "Copovidone" and the JPE monograph "Copolyvidone"
Applications: The main application is as soluble binder for granulation and as dry-binder in direct compression technology, as a film-forming agent in sprays and as pore-former in coating and taste-masking applications, as well as solubilizer in hot melt extrusion processes.
Solubility: Kollidon® VA 64 readily dissolves in all hydrophilic solvents. Solutions of more than 10% concentration can be prepared in water, ethanol, isopropanol, methylene chloride, glycerol and propylene glycol It is less soluble in ether, cyclic, aliphatic and alicyclic hydrocarbons.

Learn more about Kollidon® VA64

Portfolio Overview

Focusing on your needs with platform solutions

Download Center

Looking for application guides, technical and scientific posters, brochures or technical Information? Visist our download Center.
Product Product Details
Kollidon® VA 64 Information & Certificates
Kollidon® VA 64 Information & Certificates

Related Process Technologies

Related Applications

Related Solution Platforms