A polymeric multi-talent suitable for a large variety of applications, i.e. as thickening agent and gel former and as a co-emulsifier and viscosity enhancer in creams and liquid emulsions.
Kolliphor® P 407 is used primarily as thickening agent and gel former, as well as co-emulsifier and consistency enhancer in creams and liquid emulsions. For certain active substances such as nifedipine, naproxen and fenticonazole as well as for essential oils in pharmaceutical formulations Kolliphor® P 407 is also used as a polymeric solubilizer. In solid dispersions Kolliphor® P 407 can be used in physical mixing, melt granulation, spray drying and hot melt extrusion processes. Moreover, Kolliphor® P 407 is suitable for the formulation of active substances that show reduced solubility as well as chemical stability as a result of neutralization of gel formulations. Thanks to its ability to affect viscosity, it may also be used as stabilizer for topically administered suspensions and is used in tooth-pastes, gargles and mouthwashes. As dissolution enhancer, lubricant & wetting agent particularly Kolliphor® P 407 is specifically suitable for wet granulation processes.
|Former trade name:||Lutrol® F 127|
|Regulatory Status:||Kolliphor® P 407 meet the requirements of the current USP-NF monographs and European Pharmacopoeia family monograph Poloxamer: Ph. Eur., USP-NF: Poloxamer 407. Kolliphor ® P 407 products are also JPE certified (Japanese Pharmaceutical Excipients): Polyoxyethylene (196) Polyoxylpropylene (67) glycol|
Learn more about Kolliphor® P 407
|Kolliphor® P 407||Information & Certificates|
|Kolliphor® P 407 Geismar||Information & Certificates|