Global
Excipients for Drug Formulation

Kolliphor® P188

Flexible excipient to overcome a wide range of pharmaceutical challenges that provide formulators with increased efficiency and added functionality.

Kolliphor® P 188 is an poloxamer that enables and enhances a wide range of functional applications. For instant and modified release applications, Kolliphor® P 188 can act as a stabilizer in oral suspensions. In formulations that include poorly soluble actives, Kolliphor® P 188 can improve solubility, absorption and bioavailability. Corresponding dosage forms can then be processed by melting or granulation. Kolliphor® P 188 serves as a plasticizing agent, a solubilizer and an emulsifier, supporting both solid and liquid dispersions, as well as emulsions and micro-emulsions. Kolliphor® P 188 can also act as a co-emulsifier in creams and emulsions for skin delivery applications.

Kolliphor® P 188 can be used as an emulsifier and solubilizer, as a dispersing and wetting agent for solid dispersions and also to improve solubility, absorption and bioavailability of poorly soluble actives. It also is utilized as a co-emulsifier in creams, emulsions and as a suspension stabilizer and tablet lubricant. As dissolution enhancer, lubricant and wetting agent it is particularly suitable for wet granulation.

Our Kolliphor® Portfolio

  • BASF’s unparalleled portfolio of solubilizers and emulsifiers for topical products offers you the perfect solution, whatever the application or formulation type
  • Our innovations include new solubilizers that enhance bioavailability of active ingredients
  • The high performance and safety of BASF products is backed by comprehensive documentation – so you know you can rely on us
  • Our flexible Kolliphor® solutions can be used for hot-melt and spray-drying processes
  • BASF Poloxamers offer better solubilizing properties compared to HPMC, PVP and cyclodextrins. Also, our Poloxamers are non-ionic and less irritating
Product Details
Chemical name: Poloxamer
Former trade name: Lutrol® F 68
CAS-No: 9003-11-6
Regulatory Status: Meets requirement of Ph. Eur., USP / NF:
Poloxamer 188; JPE: Polyoxyethylene (160)
Polyoxylpropylene (30) glycol.

Learn more about Kolliphor® P 188

Portfolio Overview

Focusing on your needs with platform solutions

Download Center

Looking for application guides, technical and scientific posters, brochures or technical information? Visit our Download Center.
Product Product Details
Kolliphor® P 188 Information & Certificates
Kolliphor® P 188 Geismar Information & Certificates

Related Process Technologies

Related Applications

Related Solution Platforms