Excipients for Drug Formulation

Kolliphor® PS 60

Kolliphor® PS 60 is used as an emulsifier or co-emulsifier in topical pharmaceutical applications like creams and lotions and as non-ionic solubilizer in solid, semi-solid and liquid dosage forms or as foam stabilizer

Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. They are non-ionic surfactants and emulsifiers derived from polyethoxylated sorbitan and stearic or oleic acid. Polysorbates are mainly used as a solubilizer, emulsifier or suspension stabilizer for pharmaceutical application.

The choice of emulsifiers for specific applications depends on the desired properties of the formulation (i.e. stability, viscosity, skin feel and API), or on the desired processing technology (i.e. PIT, hot or cold processing).

Why choose Kolliphor® PS 60?

  • Suitable for cold processing of semi-solid dosage forms
  • Suitable for solid, semi solid and liquid dosage forms
  • Good skin tolerance and broad pH range
  • Fully approved – quality you can trust

Processing at room temperature to save time and energy

Besides the well known emulsifying process with two hot phases there is also the possibility to formulate an emulsion with a processing temperature at room temperature. The processing of O/W emulsions at room temperature has several significant benefits. For example, it is no longer necessary to heat the water and oil phase to 70-80 °C. This saves considerable amounts of energy and reduces the production time as the cooling step is eliminated. Another very important advantage is that head-sensitive APIs can be added to the emulsion at any point. Kolliphor® PS 60 is very suitable for this kind of application.

Application fields of Kolliphor® PS 60

  • O/W emulsifier
  • Oral solid dosage forms
  • Semi-solid dosage forms
  • Cold processing of semi-solid dosage forms
  • Liquid dosage forms
  • Foam stabilizer
Product Details
Previous name: Polysorbate 60 PH
CAS-No.: 9005-67-8
Regulatory Status: Ph. Eur, USP/NF, JPE: Polysorbate 60
General characterization: Kolliphor® PS 60 is a yellowish-brown gelatinous mass which becomes a clear liquid at temperatures above 25 °C.
Skin Tolerance: Our Kolliphor® PS types have a good skin tolerance.
Raw material origin: All Kolliphor® PS grades are based on vegetable and synthetic raw materials.

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