Kollisolv® PEG 8000
A high molecular polyethylene glycol (macrogol) mainly used as solvent for oral, topical and parenteral preparations.
Polyethylene glycols (PEGs) have been used in pharmaceutical applications for over 50 years, giving this inactive ingredient a wide acceptance. Kollisolv® PEG 8000 is a high molecular polyethylene glycol (macrogol) mainly used as solvent for oral, topical and parenteral preparations. The high molecular weight PEG is soluble in water and organic solvents such as alcohols. It can be blended with other PEG molecular weights to achieve the desired properties, i.e. viscosity. Kollisolv® PEG 8000 will not become rancid and will not support microbial growth, even in aqueous solutions.
Why use Kollisolv® PEG 8000?
- Unique properties such as low order of toxicity, solvent capabilities, blandness, water solubility
- Soluble in water and organic solvents
- Can be blended with other PEG molecular weights to achieve the desired properties
- Will not become rancid and will not support microbial growth
- Wide acceptance in pharmaceutical application for over 50 years
Major Applications of Kollisolv® PEG 8000
Applications in oral liquid formulations
Kollisolv® PEG 8000 is used as complexate with APIs for solubilization and taste masking in liquid formulations.
Application in skin delivery
As consistency factor and viscosity enhancer Kollisolv® PEG 8000 forms anhydrous, hydrophilic ointments in combination with lower molecular weight PEGs. It is also suitable as matrix in suppositories.
| Product Details | |
| Chemical Name: | Poly(ethylene glycol) |
| CAS-No: | 25322-68-3 |
| Former product name: | Pluriol® E 8000, Lutrol® E 8000 |
| Product characteristics: | White or almost white solid with a waxy or paraffin-like appearance. Very soluble in water and in methylene chloride, very slightly soluble in alcohol, practically insoluble in fatty oils and mineral oils. |
| Regulatory Status: | USP/NF: Polyethylene glycol 8000 |
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