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Excipients for Drug Formulation
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Excipients for Drug Formulation

Kollisolv® PG

Manufactured under cGMP, Kollisolv® PG (1,2-propyleneglycol) can used across a wide range of applications, i.e. as plasticizer, solvent or co-solvent, stabilizer, or as carrier for emulsifiers.

Kollisolv® PG (1,2-propyleneglycol) is manufactured in line with the current Good Manufacturing Practices (cGMP, according to ICH Q7A guideline) as a high purity grade. It is therefore suitable for any approved application. 

Benefits of Kollisolv® PG

  • High purity premium solvent
  • Suitable for a large variety of applications

Kollisolv® PG is used in a variety of pharmaceutical formulations:

  • As a preservative
  • As a carrier for emulsifiers and as a vehicle for flavours
  • As an extractant for active principles from natural products
Product Details
Chemical name: 1,2 Propandiol, (RS)-propane- 1,2 diol
INCI name: Propylene Glycole
Compendial name: Ph. Eur., USP/NF, JP: Propylene Glycol
CAS-No: 57-55-6
Regulatory Status: Meets current Propylene Glycol USP, Ph. Eur., JP, FCC monographs. The Compliance with the Directive 95/2/EC (E 1520), which regulates human food additives other than colours and sweeteners, is verified on random samples.
Properties: Kollisolv® PG is a clear, colourless viscous liquid of low volatility with a boiling range of 185 – 189 °C. It is odourless, neutral and hygroscopic. It is miscible in all proportions with water, lower alcohols, esters and ketones. Kollisolv® PG is a germicide of approximately equal strength to ethanol. In solutions it suppresses the growth of microorganisms. The concentration required depending on the species, though generally 15 – 30% Kollisolv® PG in the solution achieves the desired effect.

Learn more about Kollisolv® PG

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Further applications

Veterinary

BASF offers a broad portfolio for veterinary industry needs, including vitamins, Omega 3 and excipients with high quality and safety for the animals.

Foams

BASF offers wide range of excipients for topical formulations enabling you to create the ideal skin delivery solution for your foam formulation. By extensively analyzing, refining and enhancing the sensorial effects of each ingredient class, we can help you to create products that increase patient compliance. We are committed to maintaining the highest level of quality. At the same time, we have focused on improving the mildness of formulations. Our range of solubilizers support effective delivery of the target API – the number-one priority when designing any dermatological product.

Liquid Dispersions, Solutions & Emulsions

A common way to improve the solubility of active ingredients is to formulate them in a liquid form - i.e. dispersion, solution, suspension or emulsion. Although each approach has its differences, they all share the need for functional excipients. BASF offers a comprehensive range of trusted functional excipients to make them work.

Solid Dispersions

In a solid dispersion the drug is dispersed in a carrier with the system appearing to be in a solid state. Target is an increase in solubility & bioavailability. BASF offers both an comprehensive portfolio and process expertise to consult you in finding the best formulation for your poorly soluble drug using a solid dispersions.

Suppositories

BASF offers a variety of matrix builders, solvents and emulsifiers suitable for suppositories.

Topical Polymeric Films

BASF offers a number of film formers and plasticizers for topical formulations enabling you to create the ideal skin delivery solution for your topical polymeric film formulation.

Transdermal Patches

BASF offers a variety of polymeric matrix formers and solvents suitable for transdermal patch formulations.

Related Production Processes

Coating / Layering

Solid oral dosage forms are coated to apply a range of functions: from attractive colored instant-release coatings or robust taste-masking to functional coatings defining enteric or sustained release. BASF offers all major coating types plus as well as plasticizers for your successful coating formulation.

Related Solution Platforms

Instant & Modified Release Platform

BASFs rich portfolio of instant and modified release solutions offers an unprecedented range of functionality.

Skin Delivery Platform

The perfect solution for every skincare challenge.

Softgels Platform

Functional solutions for all soft gel parts – fill, shell and coating.

Solubilization Platform

Effective solubilization in solid & liquid dosage forms.

Softgel Coatings

Customized solutions for the effective coatings of softgels to provide enteric sustained release and moisture protection.

Softgels: Capsule Fill

At BASF we offer a comprehensive range of high quality functional excipients, vitamins and omega-3 fish oils to support you in finding the right capsule fill for your formulation needs. This unique combination of products builds a bridge between dietary supplement and pharmaceutical products.