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Excipients for Drug Formulation

Kollisolv® PYR

Solvent for injectables and oral formulations for animal health.

Kollisolv® PYR (2-Pyrrolidone) is approved for the use in veterinary medicines. The product is mainly used as a solvent for intravenous applications or topical preparations. It has also been suggested for use in human pharmaceutical formulations as solvent in parenteral, oral, and topical applications. In topical applications, Kollisolv® PYR appears to be effective penetration enhancer. Pyrrolidone has also been investigated for their application in controlled-release depot formulations. Kollisolv® PYR shows strong antimicrobial effectiveness against gram-positive and gram-negative bacteria and moulds. This results in additional preservation of the application formulation possibly no longer being necessary.

Benefits of Kollisolv® PYR

  • Approved solvent for veterinary use in injectables & oral formulations
  • Versatile solvent with broad miscibility for topical application
  • Rigorously tested – ensuring exceptional quality

Major Applications of Kollisolv® PYR

Product Details
Chemical name: 2-Pyrrolidone
Former product name: Soluphor® P
CAS-No: 616-45-5
Regulatory status: Ph. Eur., USP / NF, JP: Pyrrolidone

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