Global
Excipients for Drug Formulation
Kolliwax® GMS II
A solvent for oral, topical applications, co-emulsifier and low HLB surfactant, structure-building consistency factor for semi-solids and a viscosity enhancer. It also hardens suppository formulations and adjust their melting points.
Kolliwax GMS II is widely used as a co-emulsifier and consistency building factor. On the account of its consistency giving characters it is mainly used for the viscosity adjustment in pharmaceutical O/W emulsions. Kolliwax® GMS II is a white to slightly yellowish, hydrophilic wax, which is supplied as powder. BASF has in-depth knowledge about how to utilize this material and how best to manage its performance and its stability.
Why choose Kolliwax® GMS II?
- Fully approved, pharmaceutical-grade products – for a peace of mind
- Innovative solutions for better, more stable formulations
- Guaranteed performance across a wide variety of applications
Major applications of Kolliwax® GMS II
Emulsions
Kolliwax® grades can be used for all kinds of topical pharmaceutical applications such as gels, lotions and creams. All Kolliwax® grades act as consistency factors and co-emulsifiers at the same time. With their amphiphilic structure they will stabilize the surface between oil and water and will help to enhance the viscosity with building up a liquid crystalline network in the water-phase (lamellar structure).
Kolliwax® is able to stabilize W/O and O/W emulsion and will help top create a unique softness and creaminess in the end application. Kolliwax® GMS II acts as co-emulsifier and low HLB surfactant. It stabilizes the surfactant phases & emulsion droplets. It is suitable for production of emulsions & creams, ointments, gels and foams.
Consistency factor
Kolliwax® GMS II is used as structure-building consistency factor for semi-solids. It can mitigate stickiness or greasiness in emulsions, ointments and gels.
Solubilization
Kolliwax® GMS II is used as solvent for oral and topical applications. It is suitable for solutions, liquid suspensions and lipid-based drug delivery systems technologies.
Softgels
As co-emulsifier and viscosity enhancer Kolliwax® GMS II is used in capsule fill formulations.
Suppository mass
Suppository formulations can be hardened and adjusted in their melting point by the addition of Kolliwax® GMS II.
| Product Details | |
| Chemical name | Glycerol Monostearate |
| Former product name | Cutina® GMS V PH |
| CAS No. | 85251-77-0 |
| Raw material origin | Kolliwax® GMS II is based on vegetable and synthetic raw materials. |
| Regulatory status | Ph. Eur: Glycerol Monostearate 40-55 (type II) USP/NF: Mono- and Di-glycerades |
Learn more about Kolliwax® GMS II
Webinar (on demand)
Thermal Sintering for Controlled Drug Release of Hydrophilic Drugs
-
1
