Excipients for Drug Formulation

Kolliwax® GMS II

A solvent for oral, topical applications, co-emulsifier and low HLB surfactant, structure-building consistency factor for semi-solids and a viscosity enhancer. It also hardens suppository formulations and adjust their melting points.

Kolliwax GMS II is widely used as a co-emulsifier and consistency building factor. On the account of its consistency giving characters it is mainly used for the viscosity adjustment in pharmaceutical O/W emulsions. Kolliwax® GMS II is a white to slightly yellowish, hydrophilic wax, which is supplied as powder. BASF has in-depth knowledge about how to utilize this material and how best to manage its performance and its stability.

Why choose Kolliwax® GMS II?

  • Fully approved, pharmaceutical-grade products – for a peace of mind
  • Innovative solutions for better, more stable formulations
  • Guaranteed performance across a wide variety of applications

Major applications of Kolliwax® GMS II

Kolliwax® grades can be used for all kinds of topical pharmaceutical applications such as gels, lotions and creams. All Kolliwax® grades act as consistency factors and co-emulsifiers at the same time. With their amphiphilic structure they will stabilize the surface between oil and water and will help to enhance the viscosity with building up a liquid crystalline network in the water-phase (lamellar structure).

Kolliwax® is able to stabilize W/O and O/W emulsion and will help top create a unique softness and creaminess in the end application. Kolliwax® GMS II acts as co-emulsifier and low HLB surfactant. It stabilizes the surfactant phases & emulsion droplets. It is suitable for production of emulsions & creams, ointments, gels and foams.

Kolliwax® GMS II is used as structure-building consistency factor for semi-solids. It can mitigate stickiness or greasiness in emulsions, ointments and gels.

Kolliwax® GMS II is used as solvent for oral and topical applications. It is suitable for solutions, liquid suspensions and lipid-based drug delivery systems technologies.

As co-emulsifier and viscosity enhancer Kolliwax® GMS II is used in capsule fill formulations.

Suppository formulations can be hardened and adjusted in their melting point by the addition of Kolliwax® GMS II.

Product Details
Chemical name Glycerol Monostearate
Former product name Cutina® GMS V PH
CAS No. 85251-77-0
Raw material origin Kolliwax® GMS II is based on vegetable and synthetic raw materials.
Regulatory status

Ph. Eur: Glycerol Monostearate 40-55 (type II)

USP/NF: Mono- and Di-glycerades

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