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Excipients for Drug Formulation

Kolliwax® S

Kolliwax® S can be used for various oral solid as well as semi-solid dosage forms. Kolliwax® S can be used as a lubricant in oral dosage forms, matrix forming agent in sustained-release dosage forms, emulsifying and solubilizing agent in topical formulations and hardening agent in glycerin suppositories.

Why choose Kolliwax® S?

  • Fully approved, pharmaceutical-grade products – for your peace of mind
  • Effective alternative to magnesium stearate as lubricant
  • Guaranteed performance across a wide variety of applications
  • Compatible to a large number of actives
  • No metallic taste development

Major Applications of Kolliwax® S

Lubricants prevent ingredients from clumping together and from sticking to the tablet punches or capsule filling machine. Lubricants also ensure that tablet formulation and ejection can occur with low friction.

Common minerals like silica or talk, and fats, i.e. vegetable stearin, magnesium stearate or stearic acid are the most frequently used lubricants in tablets or hard gelatin capsules. Lubricants are added in small quantities to tablet and capsule formulations to improve certain processing characteristics.

In tablet formulations, Kolliwax® S can be used as a lubricant as an effective alternative to magnesium stearate. Stearic acid is compatible to a large number of actives and does not provide a metallic taste. When used as lubricant Kolliwax® S is blended to granular phase. The selection of the grade depends on formulation properties.

Kolliwax® S can also be used as moisture protective component for coating films together with hydroxypropoylmethylcellulose (HPMC) and microcrystalline cellulose (MCC).

Suppository formulation containing high amount of glycerol can be hardened by the addition of Kolliwax® S.

 

 

Kolliwax® S can be used as a consistency factor and co-emulsifier in topical pharmaceutical applications. The typical concentration in emulsions and creams is about 1-5%. As a structure-building consistency factor with dry feel it forms a crystalline barrier on skin.

For softgel formulations Kolliwax® S can be used as emulsifying, viscosity enhancer and solubilizing agent or as solid lubricant for capsules shells.

Learn more about Kolliwax® S

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