Excipients for Drug Formulation

Ludipress® – Enabling efficient direct tabletting

Ludipress® – a granulate that means quicker, easier, and more cost-effective tabletting. With Ludipress®, you save precious time on developing, analyzing and blending. You simply add your active ingredient, a lubricant, and compress your tablets. It is that easy.

What makes Ludipress so effective?

Ludipress® is suitable for low-dosage active ingredients. The excipient is based on extensive research and development, aimed at creating excipients that enable faster, more efficient manufacturing – while delivering perfect results every time.

Ludipress® is created by a sophisticated production process. It is a unique three-in-one system, combining the strengths of three excipients: lactose as carrier and filler, binding agent Kollidon® 30, and Kollidon® CL – one of the best disintegrants on the market. Together, they form a granulate with excellent flowability, low hygroscopicity, plus outstanding binding power. This enables you to quickly and easily create homogeneous mixtures with your active ingredient, and to directly compress high-quality tablets.

Ludipress® – enabling efficient direct tableting

  • A three-in-one system comprising filler, binder and disintegrant with very low hygroscopicity and excellent flowability
  • US FDA approved and IID-listed (inactive ingredient database)
  • Accelerated product development and process validation
  • Reduced costs – for storage, production and analysis
  • Quick and easy tablet compression resulting in outstanding tablets with rapid disintegration in spite of ideal hardness, low friability and fast active ingredient release
Product Details
Chemical name Lactose, povidone, crospovidone
CAS-No. 5989-81-1 + 9003-39-8
Regulatory Status The formulated ingredients lactose monohydrate, Kollidon® 30 and Kollidon® CL correspond to the current monographs in Ph.Eur., USP/NF and JP. In addition, Ludipress® is approved by FDA and IID listed.
Applications The main application is for direct compression, but is also suitable as a filler for hard gelatine capsules.

How direct compression with Ludipress® saves you time and money.

Ludipress® – excellent tablets every time.

Ludipress® is a granulate that supports direct-compression tableting, making your life much easier. And giving you peace of mind: because you know you can be sure of great results, each and every time.

Ludipress® combines the three functionalities of a fillerbinder and disintegrant in a ready-to-use excipient for tabletting using the direct compression technology. Ludipress® yields tablets of low friability, even with low compression forces, and irrespective of tableting speed. Kollidon® CL, one of the most effective disintegrants around, means tablets start to disintegrate within moments – despite superb hardness.

Ludipress® yields exceptionally high-quality tablets:

The following examples show how tablets based on Ludipress® perform in hardness tests.

The hardness of tablets produced on a state-of-the-art rotary press is not influenced by the press’s operating speed. This is illustrated by the results gained with a Glibenclamid formulation.
The unique composition of Ludipress yields tablets with excellent hardness and compression properties

Learn more about Ludipress®

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