Disintegration for solid oral dosage forms – functional solutions from BASF
A disintegrant ensures that a solid oral dosage form quickly breaks into smaller fractions in order to ensure a fast release of the drug. BASF offers disintegrants across a broad range of particle sizes, making any type of desired formulation possible.
Disintegrants disperse a dosage form into smaller particles as soon as they reach an aqueous environment, i.e. through swelling. With this breakdown into smaller units, the medium is exposed to more of the active ingredient surface, which then dissolves to be adsorbed. Without the disintegrant, a significant amount of a drug could ultimately pass the body without ever getting to action.
Learn more about our solutions for disintegration