Functional solutions for formulations with instant drug release

An instant release profile enables the immediate beginning of the dissolving process of a dosage form once it has been swallowed and reached the patient’s stomach. BASF offers highly functional, instant release polymers.

Instant drug release is the most commonly used release profile for solid oral dosage forms. It means to release the active ingredient immediately when it reaches the stomach. Since most solid dosage forms, particularly tablets, receive a coating to provide them with basic protection from environmental factors as well as pleasant appearance, a formulator needs to make sure that this coating dissolves just as fast.

We offer a comprehensive range of functional materials that provide exactly this characteristic. Whether you are looking for a high efficiency instant release coating, for moisture protection or for easy-to-apply yet very effective taste-masking – we have a solution.

BASFs instant release solutions are characterized by

High efficiency, thus low cost-of-ownership
Robust processing and easy-of-use
Applicability in aqueous media, no organic solvents required
Highly functional, cutting-edge instant release polymer portfolio
Effective and easy to apply taste-masking and moisture protection solutions

And of course, we also offer a wide range of functional solutions to create instant release pores in sustained release matrices or coatings.

Discover more about BASF's solutions for instant release dosage forms.

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A recent advancement in orally disintegrating formulations

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BASF pharma solutions for orally disintegrating tablets

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Focusing on your needs with platform solutions

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Our range of products that can be used to design instant release profiles for your dosage form

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Kollicoat^® IR

As instant release film former, Kollicoat^® IR combines exceptional coating quality with simple, robust processing. As wet binder, it combines powerful binding with no peroxides at all. And all those characteristics also make it a great pore former for sustained release formulations.

Kollicoat^® Protect

Effective and reliable moisture protection for your active ingredients

Kollicoat^® Smartseal 30 D

Breaking new ground in taste masking and moisture protection

Kollicoat^® SR 30 D

Precise, pH-independent sustained release for multiple applications

Kollidon^® 12 PF

Low-molecular grade Kollidon^®, intended for use as solubilizing agent, dispersant and crystallization inhibitor particularly for injectables. In addition applicable as pore former in solid dosage forms and viscosity enhancer in parenterals.

Kollidon^® 30

Our medium-molecular povidone is used in endless ways in pharmaceutical formulations - as binder, pore former, stabilizer, thickener, as solubilizing agent, crystallization inhibitor and many more. And with our trusted quality, it will always serve exactly what you intended it for.

Kollidon^® VA64

Kollidon^® VA64 is used in granulation and as a dry binder in tablets, capsules and granules, as a film-forming agent in tablet coatings and subcoatings, and as a film-forming agent in topical sprays. Soluble copovidone widely used for instant release formulation and is suitable in hot-melt extrusion processes.

Binding

BASF offers the most comprehensive range of binders for any formulator challenge – from formulating highly sensitive drugs to establishing efficient continuous processing.

Coating / Layering

Solid oral dosage forms are coated to apply a range of functions: from attractive colored instant-release coatings or robust taste-masking to functional coatings defining enteric or sustained release. BASF offers all major coating types plus as well as plasticizers for your successful coating formulation.

Film Forming

In formulation processes film formers provide a range of functionalities via a coating layer. BASF offers a full range of highly efficient film formers for all dosage forms.

Instant & Modified Release Platform

BASFs rich portfolio of instant and modified release solutions offers an unprecedented range of functionality.

Matrices & Fillers

BASF offer specific highly functional matrix formers as well as a selection of ready-to-use tablet and ODT bases that include filler and all other necessary components.

Moisture Protection

BASF offers moisture protective coatings that active ingredients remain unaffected from environmental moisture across its lifetime.

Pore Forming

BASF offers a whole range of pore formers that can be used to tune sustained drug release in almost endless ways.

Softgel Coatings

Customized solutions for the effective coatings of softgels to provide enteric sustained release and moisture protection.

Softgels Platform

Functional solutions for all soft gel parts – fill, shell and coating.

Taste Masking

Whether you are looking for taste masking in a solid or a liquid dosage form, BASF has a whole range of solutions at hand.

Instant Release

Instant & Modified Release