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Excipients for Drug Formulation
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Excipients for Drug Formulation
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Excipients for Drug Formulation

Functional solutions
for matrices & fillers

Global
Excipients for Drug Formulation

Matrices & fillers – our functional solutions

When it comes to providing structure or simply volume to solid oral dosage forms, matrices and fillers are used. BASF offer specific highly functional matrix formers as well as a selection of ready-to-use tablet and ODT bases that include filler and all other necessary components.

In the area of Instant & Modified Release, the common application for matrices is to create a sustained release profile for the active ingredient. In this approach, the drug is embedded in an insoluble matrix out of which it can steadily migrate throughout its passage through the body. Kollidon® SR and Kollicoat® SR 30 D are our leading sustained release matrix formers providing an extensive design space for your desired relase profile. Increase your options with our extensive range of pore formers. 

In the area of fillers, we offer you a selection of co-processed, multifunctional ready-to-use solutions that will allow you to create a range of solid dosage forms without having to invest and engage in own development.

Benefit from our specialized solutions for matrices and ready-to-use bases

  • Extensive design space for sustained release matrices
  • Ready-to-use bases for tablets, lozenges, chewables, effervescents
  • Trusted functionality for your immediate formulation development

When time to market and trusted quality is key, you can rely on the following products:

Ludipress® for tablets

Ludipress® – a granulate that means quicker, easier, and more cost-effective tabletting. With Ludipress®, you save precious time on developing, analyzing and blending. You simply add your active ingredient, a lubricant, and compress your tablets. It is that easy.

Ludiflash® for ODTs

Ludiflash® is an all-in-one solution: filler, binder, and disintegrant that provides tablets with exceptional hardness and low friability, while giving your ODT an outstandingly creamy mouthfeel. It lowers storage and analytical costs and accelerates product development and process validation. Tableting is possible with any conventional equipment and any preferred packaging type. Ludiflash® enhances the cohesion with API‘s and is compatible with many typical ingredients in standard formulations.

Ludipress® LCE for lozenges, chewables & effervescents

Ludipress® LCE is a ready-to-use direct compression solution for lozenges, chewables and effervescent tablet. The white, free-flowin granulate that means quicker, easier, and more cost-effective tableting. With Ludipress® LCE, you save precious time on developing, analyzing and blending. You simply add your active ingredient, a lubricant, and compress your tablets. It is that easy.

Learn more about our matrices and fillers solutions for solid oral dosage forms

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Instant & Modified Release matrices & filler solutions from BASF

Kollicoat® SR 30 D

Precise, pH-independent sustained release for multiple applications

Kollidon® SR

Direct Compression Sustained Release

Kolliwax® S Fine

Kolliwax® S Fine can be used for various oral solid as well as semi-solid dosage forms: It can be used as a lubricant in oral dosage forms, matrix forming agent in sustained-release dosage forms, emulsifying and solubilizing agent in topical formulations and hardening agent in glycerin suppositories. Kolliwax® S Fine is particularly suitable for sensitive APIs.

Ludiflash® – The taste of success

Ludiflash® is an all-in-one solution: filler, binder, and disintegrant that provides tablets with exceptional hardness and low friabilit, while giving your ODT an outstandingly creamy mouthfeel. It lowers storage and analytical costs and accelerates product development and process validation. Tableting is possible with any conventional equipment and any preferred packaging type. Ludiflash® enhances the cohesion with API‘s and is compatible with many typical ingredients in standard formulations.

Ludipress®

Ludipress® – a granulate that means quicker, easier, and more cost-effective tableting. With Ludipress®, you save precious time on developing, analyzing and blending. You simply add your active ingredient, a lubricant, and compress your tablets. It is that easy.

Ludipress® LCE

A ready-to-use direct compression solution for lozenges, chewables and effervescent tablet.

Processes related to matrices & fillers

Direct Compression

Direct compression (DC) is the most economic way to produce a tablet as it is the shortest and most direct way to get from powder mix to final dosage form. BASF offers all functional excipients to successfully develop a DC process for your drug, including key elements like appropriate binder and lubricant.

Dry Granulation

Dry granulation is a great choice to produce solid oral dosage forms if cost and process efficiency are essiential. BASF offers the most effective dry binders available, along with all other functional materials and expertise required to help you develop your process successfully.

Wet Granulation

BASF offers the key functional materials required to achieve great wet granulation results.