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Excipients for Drug Formulation
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Excipients for Drug Formulation
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Excipients for Drug Formulation

Functional solutions for
plasticizing from BASF

Global
Excipients for Drug Formulation

Plasticizers for coating formulations – functional solutions from BASF

In pharmaceutical coatings, plasticizers are used to allow initial film forming and to achieve the right amount of film flexibility to avoid cracking and peel-off. We offer you a comprehensive selection of pharma plasticizers with trusted functional performance.

Plasticizers are a common requirement for many pharmaceutical coatings. Except for 3rd-generation coating polymers like Kollicoat® IR, where the plasticizer is already integrated into the molecule structure, a plasticizer is added to the coating spray formulation to achieve the right film flexibility.

Why plasticizers from BASF?

  • Wide selection for your formulation flexibility
  • Trusted functional performance

Primary targets of plasticizing process

The plasticizing process aims at two primary targets:

  • It prevents cracks in and consequent peel-off of the film during storage, which would harm both its functionality and its appeal to the patient.

Learn more about our plasticizer solutions for coating formulations

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Our wide choice of plasticizers for your formulation

Kolliphor® RH40

Non-ionic oil-in-water solubilizer and emulsifying agent

Kollisolv® GTA

A hydrophilic plasticizer used in both, aqueous and solvent-based polymeric coating of capsules, tablets and granules. Also used as a solubilizer and solvent as well as a humectant.

Kollisolv® P 124

The only monographed poloxamer that is liquid at room temperature – making it ideal for liquid dosage forms. It is used for liquid-filled softgel capsules as a dispersion medium for APIs, or as plasticizer for tablet formulations.

Kollisolv® PEG 300

Excellent solvents for a large number of substances that do not readily dissolve in water

Kollisolv® PEG 400

Excellent solvents for a large number of substances that do not readily dissolve in water

Kollisolv® PG

Manufactured under cGMP, Kollisolv® PG (1,2-propyleneglycol) can used across a wide range of applications, i.e. as plasticizer, solvent or co-solvent, stabilizer, or as carrier for emulsifiers.

Related Process Technologies

Coating / Layering

Solid oral dosage forms are coated to apply a range of functions: from attractive colored instant-release coatings or robust taste-masking to functional coatings defining enteric or sustained release. BASF offers all major coating types plus as well as plasticizers for your successful coating formulation.