Functional solutions for
plasticizing from BASF

Plasticizers for coating formulations – functional solutions from BASF

In pharmaceutical coatings, plasticizers are used to allow initial film forming and to achieve the right amount of film flexibility to avoid cracking and peel-off. We offer you a comprehensive selection of pharma plasticizers with trusted functional performance.

Plasticizers are a common requirement for many pharmaceutical coatings. Except for 3^rd-generation coating polymers like Kollicoat^® IR, where the plasticizer is already integrated into the molecule structure, a plasticizer is added to the coating spray formulation to achieve the right film flexibility.

Why plasticizers from BASF?

Wide selection for your formulation flexibility
Trusted functional performance

Primary targets of plasticizing process

The plasticizing process aims at two primary targets:

It reduces the glass transition temperature of the film forming polymer to allow the coating process to take place at reasonable temperatures.

It prevents cracks in and consequent peel-off of the film during storage, which would harm both its functionality and its appeal to the patient.

Learn more about our plasticizer solutions for coating formulations

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Our wide choice of plasticizers for your formulation

Kolliphor^® RH40

Non-ionic oil-in-water solubilizer and emulsifying agent

Kollisolv^® GTA

A hydrophilic plasticizer used in both, aqueous and solvent-based polymeric coating of capsules, tablets and granules. Also used as a solubilizer and solvent as well as a humectant.

Kollisolv^® P 124

The only monographed poloxamer that is liquid at room temperature – making it ideal for liquid dosage forms. It is used for liquid-filled softgel capsules as a dispersion medium for APIs, or as plasticizer for tablet formulations.

Kollisolv^® PEG 300

Excellent solvents for a large number of substances that do not readily dissolve in water

Kollisolv^® PEG 400

Excellent solvents for a large number of substances that do not readily dissolve in water

Kollisolv^® PG

Manufactured under cGMP, Kollisolv® PG (1,2-propyleneglycol) can used across a wide range of applications, i.e. as plasticizer, solvent or co-solvent, stabilizer, or as carrier for emulsifiers.

Related Process Technologies

Coating / Layering

Solid oral dosage forms are coated to apply a range of functions: from attractive colored instant-release coatings or robust taste-masking to functional coatings defining enteric or sustained release. BASF offers all major coating types plus as well as plasticizers for your successful coating formulation.

Functional solutions for plasticizing from BASF