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Excipients for Drug Formulation

Functional solutions for
taste masking from BASF

Instant & Modified Release

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Excipients for Drug Formulation

Taste masking for solid and liquid oral dosage forms – our functional solutions

Taste masking is necessary when a drug administered orally has an unpleasant taste. Whether you are looking for taste masking in a solid or a liquid dosage form, BASF has a whole range of solutions at hand.

Active ingredients with unpleasant taste are a challenge for formulators. Many drugs being developed are bitter in taste, yet patients and consumers generally expect a pleasant administration experience, regardless of the medication. And on the generic side, there is significant competitive pressure to ensure that your product at least does not fall short in patient compliance, if pharmaceutical marketers want to compete successfully. 

A taste masking solution for every formulation

  • Taste masking for both solid and liquid dosage forms
  • Solutions for moderate & strong taste masking depending on drug bitterness
  • Next generation taste masking for pellets & particles, enabling taste masked orally disintegrating tablets (ODT)

BASF offer taste masking solutions for solid and liquid dosage forms

Masking unpleasant taste is key for both solid and liquid dosage forms. BASF offers taste masking solutions for both. And, depending on the bitterness of your drug and the target release profile, you can choose between moderate and maximum taste masking effect.

Kollicoat® Smartseal 30 D – Active Protection

Working with a very bitter active ingredient? Or trying to taste mask small particles? Try the first aqueous dispersion of a protective polymer. Kollicoat® Smartseal 30 D is the best solution for taste masking protection, and even beyond tablets. It even allows easy and upscalable coating of pellets and particles, without being sticky. And best of all: Kollicoat® Smartseal 30 D does not have a bad smell.

Smart protection from unpleasant taste

Due to the extraordinary stability in the saliva and the specific solubility in gastric juice, Kollicoat® Smartseal 30 D ensures effective protection from unpleasant tastes in the patients mouth and rapid release and onset of action of the active ingredients in the stomach. Kollicoat® Smartseal 30 D hides bitter taste with a significantly reduced coating thickness. For example, it masks the taste of quinine hydrochloride tablets more effectively than other leading protective coatings.

Learn more about our taste masking solutions

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We offer solutions for moderate & strong taste masking for both solid & liquid dosage forms

Kollicoat® MAE 30 DP

Enteric coating with release above pH 5.5, coming as a 30 % solids content dispersion.

Kollicoat® Smartseal 30 D

Breaking new ground in taste masking and moisture protection

Kollicoat® SR 30 D

Precise, pH-independent sustained release for multiple applications

Kollidon® 25

Our medium-molecular povidone is used in endless ways in pharmaceutical formulations - as binder, pore former, stabilizer, thickener, as solubilizing agent, crystallization inhibitor and many more. And with our trusted quality, it will always serve exactly what you intended it for.

Kollidon® 30

Our medium-molecular povidone is used in endless ways in pharmaceutical formulations - as binder, pore former, stabilizer, thickener, as solubilizing agent, crystallization inhibitor and many more. And with our trusted quality, it will always serve exactly what you intended it for.

Kollidon® CL-M

Kollidon® CL-M is used as a stabilizer for oral and topical suspensions and to improve the drug release characteristics of tablets, capsules or granules. Our disintegrant with micronized particles, delivers a slight disintegration functionality when used as binder. The crosspovidone is also used as pore former in some formulations.

Kolliphor® P 407

A polymeric multi-talent suitable for a large variety of applications, i.e. as thickening agent and gel former and as a co-emulsifier and viscosity enhancer in creams and liquid emulsions.

Kolliphor® RH40

Non-ionic oil-in-water solubilizer and emulsifying agent

Kollisolv® PEG 300

Excellent solvents for a large number of substances that do not readily dissolve in water

Kollisolv® PEG 400

Excellent solvents for a large number of substances that do not readily dissolve in water

Kollisolv® PEG 8000

A high molecular polyethylene glycol (macrogol) mainly used as solvent for oral, topical and parenteral preparations.

Related pages to taste masking

Coating / Layering

Solid oral dosage forms are coated to apply a range of functions: from attractive colored instant-release coatings or robust taste-masking to functional coatings defining enteric or sustained release. BASF offers all major coating types plus as well as plasticizers for your successful coating formulation.

Orally Disintegrating Tablets (ODT)

Orally disintegrating tablets (ODT), are an innovative solid oral dosage form that is becoming more and more important in the pharmaceutical market, both for prescription and over-the-counter medications. In contrast to classical tablets, ODTs are specifically designed to disintegrate directly in the patient's mouth.