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Excipients for Drug Formulation
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Excipients for Drug Formulation
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Excipients for Drug Formulation

Functional solutions for your
softgel solubilization
formulation challenges

Solubilization Platform

Global
Excipients for Drug Formulation

Softgel Fills:
Solubility Enhancement & Emulsification

BASF offers a comprehensive range of high quality lipids, solvents and solubilizers to enhance solubility and bioavailability of poorly soluble drugs in softgel formulations.

Poorly soluble drugs are one of the major challenges pharmaceutical manufacturers are facing. More and more drugs in development exhibit low solubility. Self-emulsifying drug delivery is one option enhance solubility and bioavailability for lipophilic drugs.a comprehensive range of high quality lipids, surfactants such as emulsifiers, solubilizers and solvents for the formulation of SEDDS. Our formulation experts can provide customized solutions for your API. 

Benefits

  • Comprehensive functional portfolio for solubiliation in liquid dosage forms
  • Trusted and proven performance and safety of our products
  • Comprehensive functional portfolio for solubiliation in solid & liquid dosage forms
  • High Through put screening tools to speed up you formulation time

Selecting the right solubilization product and technology for a poorly soluble API often involves a lot of trial and error. But partnering with our experts, you can tap into their extensive solubilization expertise and experience with all key technologies. Our experts have access to industry-leading tools such as our high-throughput screening (HTS) robot. Our HTS screening tools can helo you to speed up the formulation time.

Related Solution Platform

Solubilization Platform

Effective solubilization in solid & liquid dosage forms. The right path for greater solubility and bioavailability.

Discover more about solubilization enhancement solutions for your softgel formulation

Webinar (on demand)

Practical Considerations for Overcoming Bioavailability Challenges with LBDDS...

ebook

The Formulation Complex: Unravelling the challenges and trends in formulation best practice – and why lipids and softgels are leading the way.

The Medicine Maker

From Brick Dust to Blockbuster? - Self-emulsifying lipids, and other innovative solubilizers and polymers

ebook

Current Solubilization Techniques: Insights from the BASF Solubilization Symposium

ebook

Formulation Technologies and Excipient Selection: Strategies for Improving Solubility

Portfolio Overview

Focusing on your needs with platform solutions

Download Center

Looking for application guides, technical and scientific posters, brochures or technical Information? Visit our Download Center.

Discover our products for emulsification in softgels

Kolliphor® CS 12

A non-ionic emulsifier; stable with acidic, basic and ionic excipients.

Kolliphor® CS 20

A non-ionic emulsifier with good sensory properties; stable with acidic, basic and ionic excipients.

Kolliphor® EL

BASF's non-ionic solubilizer and emulsifier for the production of semi-solid and liquid formulations of water-insoluble actives and other hydrophobic compounds.

Kolliphor® ELP

Kolliphor® ELP is a non-ionic oil-in-water emulsifier and/or solubilizer for sensitive active ingredients

Kolliphor® HS 15

A potent nonionic solubilizer

Kolliphor® P 338

A polymeric multi-talent suitable for a large variety of applications, i.e. Kolliphor® P 338 can be used as solubilizer, emulsifier and plasticizer.

Kolliphor® P 407

A polymeric multi-talent suitable for a large variety of applications, i.e. as thickening agent and gel former and as a co-emulsifier and viscosity enhancer in creams and liquid emulsions.

Kolliphor® P188

Flexible excipient to overcome a wide range of pharmaceutical challenges that provide formulators with increased efficiency and added functionality.

Kolliphor® PS 20

Kolliphor® PS 20 is a non-ionic, hydrophilic emulsifier, co-emulsifier and solubilizer for pharmaceutical preparations like emulsions and creams, gels and foams as well as softgels.

Kolliphor® PS 60

Kolliphor® PS 60 is used as an emulsifier or co-emulsifier in topical pharmaceutical applications like creams and lotions and as non-ionic solubilizer in solid, semi-solid and liquid dosage forms or as foam stabilizer.

Kolliphor® PS 80

Kolliphor® PS 80 is a non-ionic, hydrophilic emulsifier, co-emulsifier and solubilizer for pharmaceutical preparations like like emulsions and creams, gels and foams as well as softgels.

Kolliphor® RH40

Non-ionic oil-in-water solubilizer and emulsifying agent

Kollisolv® P 124

The only monographed poloxamer that is liquid at room temperature – making it ideal for liquid dosage forms. It is used for liquid-filled softgel capsules as a dispersion medium for APIs, or as plasticizer for tablet formulations.

Kolliwax® CSA 50

A fatty alcohol mixture, preferred for its stability in emulsion formulations.

Kolliwax® GMS II

A solvent for oral, topical applications, co-emulsifier and low HLB surfactant, structure-building consistency factor for semi-solids and a viscosity enhancer. It also hardens suppository formulations and adjust their melting points.

Kolliwax® HCO

Kolliwax® HCO is hydrogenated castor powder for pharmaceutical application used as consistency factor in topical formulations, as lipohphillic lubricant in tablets and capsules and as plasticizer in solid dispersions using spray drying, melt granulation or hot melt extrusion processes. Kolliwax® HCO is particularily suitable for formulation of sensitive APIs.

Kolliwax® S

Kolliwax® S can be used for various oral solid as well as semi-solid dosage forms. Kolliwax® S can be used as a lubricant in oral dosage forms, matrix forming agent in sustained-release dosage forms, emulsifying and solubilizing agent in topical formulations and hardening agent in glycerin suppositories.

Novata®

The best option for suppository masses or solid compositions.

Related Solution Platforms

Softgels Platform

Functional solutions for all soft gel parts – fill, shell and coating.

Solubilization Platform

Effective solubilization in solid & liquid dosage forms.