Excipients for Drug Formulation

Solubilization of poorly soluble active ingredients

Effective solubilization in solid & liquid dosage forms. The right path for greater solubility and bioavailability.

Poorly soluble drugs are one of the major challenges pharmaceutical manufacturers are facing. More and more drugs in development exhibit low solubility. At BASF, we offer a comprehensive range of cutting-edge solubilization polymers, and have an unparalleled understanding of the corresponding process technologies. This unique combination means that we can make sure you achieve effective solubilization across a range of dosage forms – particularly in solid dispersions.

Furthermore, BASF is a highly successful pioneer in the application of hot-melt extrusion technology in pharmaceutical production, which helps you combine effectiveness with cost efficiency.


Finding the best solubilization solution

Selecting the right solubilization product and technology for a poorly soluble API often involves a lot of trial and error. But partnering with our experts, you can tap into their extensive solubilization expertise and experience with all key technologies, such as hot-melt extrusion, spray drying, and drug layering. Our experts have access to industry-leading tools such as our high-throughput screening (HTS) robot. This puts them in an excellent position to help customers tackle their solubilization and bioavailability challenges rapidly and efficiently.

BASF delivers answers to even the toughest solubilization challenges

  • Comprehensive functional portfolio for solubiliation in solid & liquid dosage forms
  • Innovative excipients for poorly soluble APIs
  • Proven performance and safety
  • Technology leader for key technologies such as hot-melt extrusion
  • High throughput screening service Solu-HTS

Choose Your Drug Delivery System


NEW - Excipients for Parenteral Use

The parenteral application requires excipients of highest quality standards. Solubilizers and co-solvents are the most widely employed excipients in the formulation of parenterals. BASF offers a wide range of high-quality solubilization excipients and has unparalleled experience in quality and regulatory affairs, as well as solubility enhancement strategies.

Excipients for Parenteral Use

Discover our solubilization solutions

Learn more about our solubilization solutions

Self-emulsifying Drug Delivery System (SEDDS) Formulary

Self-emulsifying Drug Delivery System (SEDDS) Formulary

Product Overview

Focusing on your needs with platform solutions

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Our Highlight Products

Discover key technologies to increase bioavailability and our specific functional offer.