Creams, ointments, gels, and foams are popular topical dosage forms that are suitable for a broad range of applications

Oil/Water emulsions are used in many pharmaceutical dosage forms to solubilize active ingredients, assist in skin penetration, and increase drug bioavailability. However, formulating emulsions is notoriously challenging due to a complex interplay between multiple competing forces, often leading to unstable formulations. As a result, current formulation approaches are empirical and paint an incomplete (and often inaccurate) picture of the emulsion landscape, complicating formulation development.

Hydrophile-Lipophile Difference / Net-Average Curvature (HLD-NAC) is a new, innovative approach for rational design of pharmaceutical emulsions. In an environment where fast, efficient product design is critical, HLD-NAC principles can significantly accelerate formulation development with minimal trial-and-error.

Watch our webinar with BASF Pharma Solutions expert Connor Bilchak and learn how BASF is enabling your emulsion formulation design with state-of-the-art science!

Webinar date: Apr 29, 2025

Lipid-based pharmaceutical excipients are frequently utilized in topical semisolid dosage forms due to their versatility and multifunctionality. Despite their long history of use, lipid-based pharmaceutical excipients continue to challenge beginner and expert formulators alike as these materials must be carefully balanced in often complex mixtures to achieve efficacious dermal drug delivery. To investigate the how to leverage lipid-based excipients to build stable and cosmetically elegant topical formulations, BASF has partnered with Mark Chandler of ACT Solutions Corp. We are pleased to have Mark take part in our webinar and present his work on using various stabilization techniques to address formulation challenges through the application of co-processed, self-emulsifying systems.

Webinar date: Jun 6, 2023

In disease states such as atopic dermatitis, excipient mildness plays an essential role in topical formulation development due to the skin’s predisposition to irritation and hypersensitivity. Driven by excipient selection, the optimization of patient outcomes and compliance can be achieved through the development of mild topical formulations.

This webinar will explore ingredient mildness and tolerability in relation to sensitive skin and atopic dermatitis. We are pleased to have Dr. Fowler take part in our webinar to discuss his experience in the identification of cutaneous allergy and irritancy through patch testing.

Webinar date: Apr 13, 2021

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